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[婴儿期、儿童期及青年期肝外胆管的形态学研究]

[Morphologic studies of the extrahepatic bile ducts in infancy, childhood and youth].

作者信息

Tröbs R B, Mahnke P F

机构信息

Institut für Pathologische Anatomie, Karl-Marx-Universität Leipzig, DDR.

出版信息

Anat Anz. 1988;167(4):301-12.

PMID:3223595
Abstract

Morphology of the extrahepatic bile ducts was examined with light microscopic methods in 55 human cases from the age of 28 gestational weeks up to 19 years. We found that barrel-shaped cells, rod-shaped cells and goblet cells are obligatory components of the bile duct epithelium in infancy. Tunica fibromuscularis of extrahepatic bile ducts consists of connective tissue. Increase of collagen fibers and fibers stained by resorcin fuchsin was observed during development. Neither in hepatic bile duct nor in common bile duct a muscle layer exists. A third of all bile ducts was free of muscles. Sparse muscle bundles in the other cases seem not able to generate bile duct motility. A morphological correlate to the sphincter of Mirizzi and Bernhard we did not find. Tunica adventitia and surrounding connective tissue contain many spacious lymphatic vessels.

摘要

采用光学显微镜方法,对55例年龄从孕28周直至19岁的人体标本的肝外胆管形态进行了检查。我们发现,桶状细胞、杆状细胞和杯状细胞是婴儿胆管上皮的必备组成部分。肝外胆管的纤维肌层由结缔组织构成。在发育过程中,观察到胶原纤维和间苯二酚品红染色的纤维增多。肝内胆管和胆总管均不存在肌肉层。所有胆管中有三分之一没有肌肉。其他病例中的稀疏肌束似乎无法产生胆管蠕动。我们未发现与Mirizzi括约肌和Bernhard括约肌相关的形态学特征。外膜和周围结缔组织含有许多宽大的淋巴管。

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