Department of Dermatology, Xijing hospital, Fourth Military Medical University, 15 Changlexi Road, 710032 Xian, China.
Eur J Dermatol. 2013 Sep-Oct;23(5):614-7. doi: 10.1684/ejd.2013.2152.
Eccrine angiomatous hamartoma (EAH) is recognized as a vascular hamartoma composed of abnormal proliferation of blood vessels and eccrine glands.
We sought to investigate the immunohistochemical results of D2-40 and Prox1 in EAH in order to gain further insight into its histogenesis.
We collected 21 cases of EAH diagnosed in a dermatology department. Immunohistochemical staining of D2-40 and Prox1 was performed on all cases.
Prox1 was universally positive in the endothelial cells of proliferated vessels in all cases. D2-40 was universally positive in the endothelial cells of proliferated vessels in 3 cases, focally positive in 18 cases.
EAH is a lymphatic proliferation and therefore we suggest the name of eccrine lymphangiomatous hamartoma.
小汗腺血管错构瘤（EAH）被认为是一种由血管和小汗腺异常增生组成的血管错构瘤。
我们旨在通过研究 D2-40 和 Prox1 在 EAH 中的免疫组化结果，进一步探讨其组织发生。
我们收集了皮肤科诊断的 21 例 EAH 病例。对所有病例均行 D2-40 和 Prox1 免疫组化染色。
所有病例中，增生血管的内皮细胞均普遍表达 Prox1。3 例增生血管的内皮细胞普遍表达 D2-40，18 例局灶性阳性。
EAH 是一种淋巴管增生，因此我们建议命名为小汗腺淋巴管瘤样错构瘤。
