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哑铃形展神经鞘瘤:病例报告

Dumbbell-shaped abducens schwannoma: case report.

作者信息

Shibao Shunsuke, Hayashi Saeko, Yoshida Kazunari

机构信息

Department of Neurosurgery, Keio University School of Medicine.

出版信息

Neurol Med Chir (Tokyo). 2014;54(4):331-6. doi: 10.2176/nmc.cr2012-0304. Epub 2013 Nov 8.

DOI:10.2176/nmc.cr2012-0304
PMID:24201095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4533476/
Abstract

Schwannomas of the abducens nerve are uncommon. Nineteen cases have been reported in the literature and are classified into two types: Type 1, in the cavernous sinus, and Type 2, in the prepontine area. However, a dumbbell-shaped type has not yet been reported. Here we report the first case of a dumbbell-shaped abducens schwannoma and classify this type into a new category (Type 3). A 36-year-old woman presented with left hearing disturbance for 4 years, dizziness for 2 years, and dysphagia for 6 months. Neurological examination showed left sensorineural hearing impairment, hypesthesia in the distribution of the left first and second branches of the trigeminal nerve, left curtain sign, and gait disturbance. Computed tomography and magnetic resonance imaging revealed a dumbbell-shaped tumor located in the cavernous sinus that extended to the right cerebellopontine angle. She underwent a two-staged operation; the first operation was via ananterior transpetrosal approach for the lesion in the middle fossa and the upper part in the posterior fossa, and the second surgery was via alateral suboccipital approach for the lower part in the posterior fossa. In the first operation, the abducens nerve was sacrificed. Histological examination confirmed schwannoma. Postoperatively, hearing disturbance and ataxia were improved and complete abducens nerve paresis appeared. The dumbbell-shaped abducens schwannoma has novel clinical features, difficulty of sixth nerve preservation, and unique surgical approach.

摘要

展神经鞘瘤并不常见。文献中已报道19例,分为两种类型:1型位于海绵窦,2型位于脑桥前区。然而,哑铃形类型尚未见报道。在此,我们报告首例哑铃形展神经鞘瘤,并将此类型归为一个新类别(3型)。一名36岁女性,有4年左耳听力障碍、2年头晕及6个月吞咽困难病史。神经系统检查显示左耳感音神经性听力减退、左侧三叉神经第一和第二分支分布区感觉减退、左侧幕征及步态障碍。计算机断层扫描和磁共振成像显示一个位于海绵窦的哑铃形肿瘤,延伸至右侧桥小脑角。她接受了分期手术;第一次手术通过经岩前入路处理中颅窝及后颅窝上部病变,第二次手术通过枕下外侧入路处理后颅窝下部病变。在第一次手术中,展神经被牺牲。组织学检查证实为神经鞘瘤。术后,听力障碍和共济失调有所改善,但出现了完全性展神经麻痹。哑铃形展神经鞘瘤具有新的临床特征、保留第六神经困难及独特的手术入路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/6df9a49ece73/nmc-54-331-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/4a200bb087c7/nmc-54-331-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/d32a5a7ad3ba/nmc-54-331-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/2d392c9514b2/nmc-54-331-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/6df9a49ece73/nmc-54-331-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/4a200bb087c7/nmc-54-331-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/d32a5a7ad3ba/nmc-54-331-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/2d392c9514b2/nmc-54-331-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/4533476/6df9a49ece73/nmc-54-331-g4.jpg

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