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展神经鞘瘤:病例报告及文献复习

Abducens nerve schwannoma: case report and review of the literature.

作者信息

Park Jin Hoon, Cho Young Hyun, Kim Jeong Hoon, Lee Jung-Kyo, Kim Chang Jin

机构信息

Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea.

出版信息

Neurosurg Rev. 2009 Jul;32(3):375-8; discussion 378. doi: 10.1007/s10143-009-0203-7. Epub 2009 May 6.

Abstract

Schwannomas of the abducens nerve are extremely rare. The authors report a case with this tumor and discuss its clinical and radiographic characteristics. A 36-year-old man presented with 6-month history of diplopia. Right abducens nerve paresis was noted on neurologic examination. Magnetic resonance imaging revealed a 4-cm sized heterogeneously enhancing mass in the right cerebellopontine angle. Although schwannoma was suggested, no direct radiographic evidences regarding its origin were identified. Instead, the facial and vestibulocochlear nerve complex was found to be displaced posteriorly by the tumor on MR three-dimensional T2-weighted driven equilibrium sequence. Resection of the tumor was carried out via retrosigmoid approach. As the encapsulated partially suckable yellowish tumor was debulked and dissected, the abducens nerve was found to fan along and be attached to the medial surface of the tumor, which was cut at this point. Complete excision of the tumor was accomplished, and reanimation of the nerve was done by end-to-end anastomosis. Histologic feature was typical of schwannoma. Abducens schwannoma, although rare, should be taken into account for differential diagnosis of the cerebellopontine angle tumors. Appreciation of the characteristic clinical and radiographic features may provide an accurate preoperative diagnosis.

摘要

展神经鞘瘤极为罕见。作者报告了一例该肿瘤病例,并讨论其临床和影像学特征。一名36岁男性,有6个月复视病史。神经系统检查发现右侧展神经麻痹。磁共振成像显示右侧桥小脑角有一个4厘米大小的不均匀强化肿块。尽管提示为神经鞘瘤,但未发现关于其起源的直接影像学证据。相反,在磁共振三维T2加权驱动平衡序列上发现面神经和前庭蜗神经复合体被肿瘤向后推移。通过乙状窦后入路切除肿瘤。当将包膜完整、部分可吸出的淡黄色肿瘤分块切除并进行解剖时,发现展神经呈扇形沿肿瘤内侧表面走行并附着于其上,此时将其切断。肿瘤完整切除,并通过端端吻合进行神经修复。组织学特征为典型的神经鞘瘤。展神经鞘瘤虽然罕见,但在桥小脑角肿瘤的鉴别诊断中应予以考虑。认识其特征性的临床和影像学表现可能有助于术前准确诊断。

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