正常成人皮肤中三磷酸腺苷酶阳性朗格汉斯细胞的分布。

Distribution of ATPase-positive Langerhans cells in normal adult human skin.

作者信息

Chen H, Yuan J, Wang Y, Silvers W K

出版信息

Br J Dermatol. 1985 Dec;113(6):707-11. doi: 10.1111/j.1365-2133.1985.tb02406.x.

DOI:10.1111/j.1365-2133.1985.tb02406.x

PMID:2420351

Abstract

The distribution of ATPase-positive Langerhans cells (LC) was investigated in 117 specimens of normal adult human skin and mucosa taken from different areas of the body. Although there were significant variations in the numbers of LC in each area examined, skin from the face and neck contained the highest density of cells (976 +/- 30.93/mm2). The densities of LC in trunk skin (740 +/- 28.97/mm2), scalp (693 +/- 69.56/mm2) and arm or leg skin (640 +/- 40.95/mm2) were similar. Buccal mucosa had significantly fewer LC (567 +/- 42.94/mm2) than trunk skin, and sacrococcyx skin and palm and sole skin displayed the smallest number of these cells (267 +/- 56.14/mm2 and, 189 +/- 19.15/mm2 respectively). No ATPase-positive LC were detected in the centre of two corneal specimens.

摘要

对取自人体不同部位的117份正常成人皮肤和黏膜标本中的ATP酶阳性朗格汉斯细胞（LC）分布情况进行了研究。尽管在所检查的每个部位，LC数量存在显著差异，但面部和颈部皮肤的细胞密度最高（976±30.93/mm²）。躯干皮肤（740±28.97/mm²）、头皮（693±69.56/mm²）以及手臂或腿部皮肤（640±40.95/mm²）中的LC密度相似。颊黏膜的LC数量（567±42.94/mm²）明显少于躯干皮肤，而骶尾部皮肤以及手掌和足底皮肤中的这类细胞数量最少（分别为267±56.14/mm²和189±19.15/mm²）。在两份角膜标本的中央未检测到ATP酶阳性LC。