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基于流行病学调查的美国神经系统疾病发病率和患病率近似公式:一项荟萃分析。

Epidemiological survey-based formulae to approximate incidence and prevalence of neurological disorders in the United States: a meta-analysis.

作者信息

Borlongan Cesar V, Burns Jack, Tajiri Naoki, Stahl Christine E, Weinbren Nathan L, Shojo Hideki, Sanberg Paul R, Emerich Dwaine F, Kaneko Yuji, van Loveren Harry R

机构信息

Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida, United States of America.

出版信息

PLoS One. 2013 Oct 24;8(10):e78490. doi: 10.1371/journal.pone.0078490. eCollection 2013.

Abstract

BACKGROUND

This study aims to create a convenient reference for both clinicians and researchers so that vis-à-vis comparisons between brain disorders can be made quickly and accurately. We report here the incidence and prevalence of the major adult-onset brain disorders in the United States using a meta-analysis approach.

MATERIAL AND METHODS

Epidemiological figures were collected from the most recent, reliable data available in the research literature. Population statistics were based on the most recent census from the US Census Bureau. Extrapolations were made only when necessary. The most current epidemiological studies for each disorder were chosen. All effort was made to use studies based on national cohorts. Studies reviewed were conducted between 1950 and 2009. The data of the leading studies for several neurological studies was compiled in order to obtain the most accurate extrapolations. Results were compared to commonly accepted values in order to evaluate validity.

RESULTS

It was found that 6.75% of the American adult population is afflicted with brain disorders. This number was eclipsed by the 8.02% of Floridians with brain disorders, which is due to the large aged population residing in the state.

CONCLUSIONS

There was a noticeable lack of epidemiological data concerning adult-onset brain disorders. Since approximately 1 out of every 7 households is affected by brain disorders, increased research into this arena is warranted.

摘要

背景

本研究旨在为临床医生和研究人员创建一个便捷的参考资料,以便能够快速、准确地对脑部疾病进行对比。我们在此使用荟萃分析方法报告美国主要成人脑部疾病的发病率和患病率。

材料与方法

从研究文献中可获取的最新、可靠数据收集流行病学数据。人口统计基于美国人口普查局的最新普查数据。仅在必要时进行推断。选择每种疾病的最新流行病学研究。尽一切努力使用基于全国队列的研究。所审查的研究在1950年至2009年期间进行。汇总了多项神经学研究的主要研究数据,以获得最准确的推断结果。将结果与普遍接受的值进行比较,以评估有效性。

结果

发现6.75%的美国成年人口患有脑部疾病。这一数字被佛罗里达州8.02%患有脑部疾病的人口所超过,这是由于该州老年人口众多。

结论

关于成人脑部疾病的流行病学数据明显不足。由于大约每7户家庭中就有1户受到脑部疾病的影响,因此有必要加强对这一领域的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee5/3812041/9bb1b4fd464b/pone.0078490.g001.jpg

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