Mori A, Hiramatsu M, Kabuto H, Marescau B
Neurochem Res. 1986 Jan;11(1):37-45. doi: 10.1007/BF00965163.
Emotional stress markedly inhibited E1 mouse convulsions. Norepinephrine and dopamine levels in E1 mouse brain were hardly affected by stress, though a marked decrease in norepinephrine and dopamine levels was observed in the ddY mouse brain. The serotonin levels decreased in the E1 mouse brain in the same degree as in the ddY mouse brain. These findings suggest that the serotonergic system is involved in the inhibition of E1 mouse convulsions, through an enhanced serotonin release in the brain brought on by the emotional stress. Noradrenergic and dopaminergic systems may also be involved.
情绪应激显著抑制E1小鼠惊厥。E1小鼠脑中去甲肾上腺素和多巴胺水平几乎不受应激影响,不过在ddY小鼠脑中观察到去甲肾上腺素和多巴胺水平显著降低。E1小鼠脑中血清素水平下降程度与ddY小鼠脑相同。这些发现表明,血清素能系统通过情绪应激引起的脑中血清素释放增加参与抑制E1小鼠惊厥。去甲肾上腺素能和多巴胺能系统可能也参与其中。