Zhang Ling, Kong Hui, Chin Chien Ting, Wang Tianfu, Chen Siping
Department of Biomedical Engineering, Shenzhen University, Shenzhen 518060, China National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen 518060, China Guangdong Key Laboratory of Biomedical Information Detection and Ultrasound Imaging, Shenzhen 518060, China.
Biomed Mater Eng. 2014;24(1):1125-31. doi: 10.3233/BME-130912.
This paper proposes a method to segment the cytoplasm in cervical cell images using graph cut-based algorithm. First, the A* channel in CIE LAB color space is extracted for contrast enhancement. Then, in order to effectively extract cytoplasm boundaries when image histograms present non-bimodal distribution, Otsu multiple thresholding is performed on the contrast enhanced image to generate initial segments, based on which the segments are refined by the multi-way graph cut method. We use 21 cervical cell images with non-ideal imaging condition to evaluate cytoplasm segmentation performance. The proposed method achieved a 93% accuracy which outperformed state-of-the-art works.
本文提出了一种基于图割算法对宫颈细胞图像中的细胞质进行分割的方法。首先,提取CIE LAB颜色空间中的A*通道以增强对比度。然后,为了在图像直方图呈现非双峰分布时有效提取细胞质边界,对对比度增强后的图像进行大津多阈值处理以生成初始分割段,并在此基础上通过多路图割方法对分割段进行细化。我们使用21张成像条件不理想的宫颈细胞图像来评估细胞质分割性能。所提出的方法达到了93%的准确率,优于现有技术。