Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA.
J Am Soc Mass Spectrom. 1995 Dec;6(12):1256-61. doi: 10.1016/1044-0305(95)00552-8.
The design and performance of an electrospray ion source for a high resolution magnetic sector mass spectrometer that utilizes a heated capillary has been presented. Low pressure, high sensitivity, stable electrospray, low flow rates, and low electronic noise were important factors in achieving high resolution electrospray mass spectrometry. A unit mass resolution has been achieved for biomolecules with MW > 12,000, and an accuracy of 1.4 ppm has been achieved for the average molecular weight of bovine insulin.
已经提出了一种用于高分辨率扇形磁场质谱仪的电喷雾离子源的设计和性能，该离子源利用了加热毛细管。在实现高分辨率电喷雾质谱法时，低压、高灵敏度、稳定的电喷雾、低流速和低电子噪声是重要因素。对于 MW>12000 的生物分子，已经实现了单位质量分辨率，并且对于牛胰岛素的平均分子量，已经实现了 1.4 ppm 的精度。
