Pliasunova M M, Antelava N A, Bekaia G L, Imanishvili T Z, Kvachadze I D
Georgian Med News. 2013 Oct(223):65-71.
Along with the brief history of amide local anesthetics development, their most important properties (from the viewpoint of use in clinical dental practice), are also reviewed. In particular, some properties of most commonly used local anesthetics, such as lidocaine, mepivacaine, prilocaine, bupivacaine and articaine are analysed. The most important data concerning pharmacological mechanisms of mentioned anesthetics' action, that cause certain features and peculiarities of their clinical application are given in condensed form. Besides, some precaution measures that must be taken into account in specific clinical cases together with the history and current status of each patient are mentioned as well.
除了酰胺类局部麻醉药的发展简史外，还回顾了它们最重要的特性（从临床牙科实践应用的角度）。特别分析了最常用的局部麻醉药的一些特性，如利多卡因、甲哌卡因、丙胺卡因、布比卡因和阿替卡因。以浓缩形式给出了有关上述麻醉药作用的药理机制的最重要数据，这些机制导致了它们临床应用的某些特征和特点。此外，还提到了在特定临床病例中必须考虑的一些预防措施，以及每个患者的病史和现状。
