Gjesdal Ola, Almeida André L C, Hopp Einar, Beitnes Jan Otto, Lunde Ketil, Smith Hans-Jørgen, Lima Joáo A C, Edvardsen Thor
Department of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA; Department of Cardiology, University of Oslo and Oslo University Hospital, Oslo, Norway.
J Magn Reson Imaging. 2014 Nov;40(5):1247-51. doi: 10.1002/jmri.24485. Epub 2013 Nov 8.
To compare long axis strain (LAS) by magnetic resonance imaging (MRI) and echocardiography in a postinfarct patient population. Long axis left ventricle (LV) function is a sensitive index of incipient heart failure by echocardiography, but is less well established in MRI. LAS is an index of global LV function, which is easily assessed in cine loops provided by most cardiac MRI protocols.
In all, 116 patients (57 ± 9 years) were studied the same day using echocardiography and MRI 7.4 ± 4.1 months after a first myocardial infarction. LV length was measured in end diastole and end systole in conventional cine images with a temporal resolution of 50 msec or less, and LAS (%) was calculated as the change in LV length, relative to end diastole. Infarct mass was assessed by contrast-enhanced MRI.
LAS was progressively reduced in patients with larger infarcts, and demonstrated good correlations with infarct mass (r = 0.55, P < 0.01). There was a good agreement between LAS assessed by echocardiography and MRI (r = 0.77, P < 0.01), and between LAS by MRI and speckle tracking strain by echocardiography (r = 0.74, P < 0.01).
LAS is an index that allows measurement of LV long axis function by conventional cine MRI.
比较磁共振成像（MRI）和超声心动图测量心肌梗死后患者群体的长轴应变（LAS）。左心室（LV）长轴功能是超声心动图诊断早期心力衰竭的敏感指标，但在MRI中尚未得到充分证实。LAS是评估左心室整体功能的指标，在大多数心脏MRI协议提供的电影环中很容易评估。
共纳入116例患者（57±9岁），在首次心肌梗死后7.4±4.1个月的同一天接受超声心动图和MRI检查。在时间分辨率为50毫秒或更低的传统电影图像中测量舒张末期和收缩末期的左心室长度，并计算LAS（%），即左心室长度相对于舒张末期的变化。通过对比增强MRI评估梗死心肌质量。
梗死面积较大的患者LAS逐渐降低，且与梗死心肌质量具有良好的相关性（r = 0.55，P < 0.01）。超声心动图和MRI评估的LAS之间具有良好的一致性（r = 0.77，P < 0.01），MRI测量的LAS与超声心动图斑点追踪应变之间也具有良好的一致性（r = 0.74，P < 0.01）。
LAS是一种可通过传统电影MRI测量左心室长轴功能的指标。
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