Giaquinto S, Nolfe G
Electroencephalogr Clin Neurophysiol. 1986 Jun;63(6):540-6. doi: 10.1016/0013-4694(86)90141-0.
Forty-seven normal elderly, 16 normal subjects ranging from 40 to 60 years of age and 14 patients affected by primary dementia are studied. The EEG is recorded from different brain areas and analysed by FFT algorithm. Main results are: There is persistence of the regional distribution of the alpha frequency which is higher in occipital than in frontal leads in the normal elderly. Spectral composition in the same group keeps its typical profile with age. Alpha-dominant tracings form 68%. Values collected from the two hemispheres are similar. Therefore, no evidence is detected for a selective age effect on one side, either right or left. In the elderly group, a sex-linked difference is found. Women have less delta and more beta frequency. The opposite holds true in men. EEG slowing is typical of old age. However, in occipital leads the alpha frequency has an average of 9.46 Hz. Statistical comparison between the normal groups (middle aged vs. elderly) gives no significant results. Significant differences are seen when the normal elderly are compared with demented subjects. The data do not support the hypothesis of a continuum from aging to mental deterioration.
对47名正常老年人、16名年龄在40至60岁之间的正常受试者以及14名患有原发性痴呆的患者进行了研究。从不同脑区记录脑电图，并通过快速傅里叶变换（FFT）算法进行分析。主要结果如下：在正常老年人中，α频率的区域分布持续存在，枕叶导联中的α频率高于额叶导联。同组中的频谱组成随年龄保持其典型特征。α波为主的脑电图记录占68%。从两个半球收集的值相似。因此，未检测到对一侧（右侧或左侧）有选择性年龄效应的证据。在老年组中，发现了与性别相关的差异。女性的δ波较少，β波较多。男性则相反。脑电图减慢是老年的典型特征。然而，在枕叶导联中，α频率平均为9.46赫兹。正常组（中年与老年）之间的统计比较没有显著结果。当将正常老年人与痴呆患者进行比较时，发现了显著差异。数据不支持从衰老到精神衰退存在连续过程的假设。
