• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Towards a unified theory of immunoglobulin structure-function relations.

作者信息

Kieber-Emmons T, Kohler H

出版信息

Immunol Rev. 1986 Apr;90:29-48. doi: 10.1111/j.1600-065x.1986.tb01476.x.

DOI:10.1111/j.1600-065x.1986.tb01476.x
PMID:2422112
Abstract
摘要

相似文献

1
Towards a unified theory of immunoglobulin structure-function relations.迈向免疫球蛋白结构 - 功能关系的统一理论
Immunol Rev. 1986 Apr;90:29-48. doi: 10.1111/j.1600-065x.1986.tb01476.x.
2
Immunoglobulin structure--function correlates: antigen binding and idiotypes.免疫球蛋白结构与功能的相关性：抗原结合与独特型
Contemp Top Mol Immunol. 1983;9:169-209. doi: 10.1007/978-1-4684-4517-6_6.
3
Idiotypy and idiotypic networks: a time to redefine concepts.独特型与独特型网络：是时候重新定义概念了。
Clin Exp Immunol. 1993 Feb;91(2):193-5. doi: 10.1111/j.1365-2249.1993.tb05881.x.
4
Drastic change in idiotypic but not antigen-binding specificity of an antibody by a single amino-acid substitution.单个氨基酸替换导致抗体独特型发生剧烈变化，但抗原结合特异性未变。
Nature. 1985;315(6019):506-8. doi: 10.1038/315506a0.
5
A synthetic peptide induces a new anti-dextran idiotype.
Ann Immunol (Paris). 1984 Jan-Feb;135C(1):77-82. doi: 10.1016/s0769-2625(84)80015-x.
6
The location and expression of idiotypic determinants in the immunoglobulin variable region--II. Chain location of variable region determinants.
Mol Immunol. 1979 Jun;16(6):371-8. doi: 10.1016/0161-5890(79)90102-0.
7
The location and expression of idiotypic determinants in the immunoglobulin variable region--I. Characterization of antibodies directed against the variable region of mouse myeloma immunoglobulins 315 and 460.
Mol Immunol. 1979 Jun;16(6):361-70. doi: 10.1016/0161-5890(79)90101-9.
8
A hypothetical space-filling model of the V-regions of the galactan-binding myeloma immunoglobulin J539.
Mol Immunol. 1981 Aug;18(8):683-98. doi: 10.1016/0161-5890(81)90060-2.
9
Epibody: the image of the network created by a single antibody.表位体：由单个抗体产生的网络图像。
Immunol Rev. 1986 Apr;90:115-27. doi: 10.1111/j.1600-065x.1986.tb01480.x.
10
The minimal antigen-binding fragment of antibodies--Fv fragment.
Mol Immunol. 1991 Dec;28(12):1379-86. doi: 10.1016/0161-5890(91)90040-q.

引用本文的文献

1
The Promise of Anti-idiotype Revisited.抗独特型抗体的前景展望。
Front Immunol. 2019 Apr 12;10:808. doi: 10.3389/fimmu.2019.00808. eCollection 2019.
2
Immunoglobulin (Ig)G purified from human sera mirrors intravenous Ig human leucocyte antigen (HLA) reactivity and recognizes one's own HLA types, but may be masked by Fab complementarity-determining region peptide in the native sera.从人血清中纯化的免疫球蛋白（Ig）G反映静脉注射用人免疫球蛋白的人类白细胞抗原（HLA）反应性，并识别自身的HLA类型，但在天然血清中可能被Fab互补决定区肽掩盖。
Clin Exp Immunol. 2015 Feb;179(2):309-28. doi: 10.1111/cei.12450.
3
The promise of the anti-idiotype concept.
抗独特型概念的前景。
Front Oncol. 2012 Dec 19;2:196. doi: 10.3389/fonc.2012.00196. eCollection 2012.
4
Natural antibodies that react with V-region peptide epitopes of DNA-binding antibodies are made by mice with systemic lupus erythematosus as disease develops.随着系统性红斑狼疮病情的发展，患有该疾病的小鼠会产生与DNA结合抗体的V区肽表位发生反应的天然抗体。
Immunology. 1997 Nov;92(3):354-61. doi: 10.1046/j.1365-2567.1997.00359.x.
5
B cells and autoantibodies in the pathogenesis of lupus nephritis.B细胞和自身抗体在狼疮性肾炎发病机制中的作用
Immunol Res. 1998;17(1-2):123-32. doi: 10.1007/BF02786437.
6
Structural properties of a subset of nephritogenic anti-DNA antibodies.致肾炎性抗DNA抗体亚群的结构特性
Immunol Res. 1994;13(2-3):172-85. doi: 10.1007/BF02918278.
7
Identification of an idiotypic peptide recognized by autoantibodies in human immunodeficiency virus-1-infected individuals.在人类免疫缺陷病毒1型感染个体中鉴定出一种可被自身抗体识别的独特型肽段。
J Clin Invest. 1995 Aug;96(2):775-80. doi: 10.1172/JCI118122.
8
Construction of an extended three-dimensional idiotope map by electron microscopic analysis of idiotope-anti-idiotope complexes.通过对独特型-抗独特型复合物进行电子显微镜分析构建扩展的三维独特型图谱。
Proc Natl Acad Sci U S A. 1987 Jul;84(14):4984-8. doi: 10.1073/pnas.84.14.4984.
9
Biological mimicry of antigenic stimulation: analysis of the in vivo antibody responses induced by monoclonal anti-idiotypic antibodies.抗原刺激的生物学模拟：单克隆抗独特型抗体诱导的体内抗体反应分析。
Immunology. 1988 Jan;63(1):1-8.
10
Molecular basis for expression of the A48 regulatory idiotope on antibodies encoded by immunoglobulin variable-region genes from various families.不同家族免疫球蛋白可变区基因编码抗体上A48调节性独特型表位表达的分子基础。
Proc Natl Acad Sci U S A. 1989 Apr;86(7):2341-5. doi: 10.1073/pnas.86.7.2341.