Neusidl角膜植入器（®）用于亚洲小眼睛行Descemet膜剥离自动内皮角膜移植术的新型供体植入器的临床结果
Clinical results of the Neusidl Corneal Inserter(®), a new donor inserter for Descemet's stripping automated endothelial keratoplasty, for small Asian eyes.
作者信息
Kobayashi Akira, Yokogawa Hideaki, Sugiyama Kazuhisa
机构信息
Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa-shi, Ishikawa-ken, Japan.
出版信息
Ophthalmic Surg Lasers Imaging. 2012 Jul 1;43(4):311-8. doi: 10.3928/15428877-20120426-04. Epub 2012 May 3.
BACKGROUND AND OBJECTIVE
To present the clinical outcomes of the Neusidl Corneal Inserter (NCI) (Fischer Surgical, Imperial, MO), a new donor inserter for Descemet's stripping automated endothelial keratoplasty (DSAEK).
PATIENTS AND METHODS
Six eyes of 6 Japanese patients (mean age = 74.0 years) with endothelial dysfunction were enrolled in this prospective, non-comparative study. All patients had a small cornea of 9.0 mm or less in diameter. A donor was inserted into the eye using NCI. Intraoperative and postoperative complications, postoperative donor endothelial cell densities (ECD), and best-corrected visual acuity (BCVA) were evaluated.
RESULTS
Donor loading onto NCI was successful in all cases. No intraoperative or postoperative complications were noted. All cases reached more than 20/63 BCVA within 12 months. Mean ECD was 2,441 cells/mm(2) (mean loss = 22.1%) at 6 months and 2,159 cells/mm(2) (mean loss = 31.0%) at 12 months.
CONCLUSION
Graft insertion with NCI is safe in DSAEK with low endothelial cell loss.
背景与目的
介绍一种用于Descemet膜剥脱自动内皮角膜移植术（DSAEK）的新型供体植入器——Neusidl角膜植入器（NCI，Fischer Surgical公司，密苏里州帝国市）的临床结果。
患者与方法
本前瞻性、非对照研究纳入了6例日本患者（平均年龄 = 74.0岁）的6只患有内皮功能障碍的眼睛。所有患者的角膜直径均小于或等于9.0 mm。使用NCI将供体植入眼内。评估术中及术后并发症、术后供体内皮细胞密度（ECD）和最佳矫正视力（BCVA）。
结果
所有病例中供体均成功装载到NCI上。未观察到术中或术后并发症。所有病例在12个月内BCVA均达到20/63以上。6个月时平均ECD为2441个细胞/mm²（平均损失 = 22.），12个月时为2159个细胞/mm²（平均损失 = 31.0%）。
结论
在DSAEK中使用NCI植入移植物是安全的，内皮细胞损失较低。
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