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免疫功能正常儿童的肺炎克雷伯菌肝脓肿

Klebsiella pneumoniae liver abscess in an immunocompetent child.

作者信息

Kwon Jang-Mi, Jung Hye Lim, Shim Jae Won, Kim Deok Soo, Shim Jung Yeon, Park Moon Soo

机构信息

Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Korean J Pediatr. 2013 Sep;56(9):407-10. doi: 10.3345/kjp.2013.56.9.407. Epub 2013 Sep 30.

DOI:10.3345/kjp.2013.56.9.407
PMID:24223603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3819678/
Abstract

Klebsiella pneumoniae has emerged as a leading pathogen that causes pyogenic liver abscesses (PLAs) in Korea. K. pneumoniae liver abscess (KLA) is potentially life threatening, and the diagnosis is difficult. In developed countries, PLA is rarely observed in children and is frequently associated with disorders of granulocyte function and previous abdominal infection. We observed a case of KLA in a healthy 12-year-old boy. To our knowledge, this is the first reported case of KLA in an immunocompetent child without an underlying disease in Korea. The patient was treated with percutaneous catheter drainage and antibiotics. The catheter was placed in the intrahepatic abscess for 3 weeks and parenteral antibiotics (ceftriaxone and amikacin) were administered for 4 weeks, followed by oral antibiotics (cefixime) for 2 weeks. We reported this case to raise awareness of KLA in immunocompetent children among physicians, and to review the diagnosis, risk factors, potential complications, and appropriate treatment of KLA.

摘要

肺炎克雷伯菌已成为韩国引起化脓性肝脓肿(PLA)的主要病原体。肺炎克雷伯菌肝脓肿(KLA)有潜在生命危险,且诊断困难。在发达国家,儿童中很少观察到PLA,且其常与粒细胞功能障碍和既往腹部感染相关。我们观察到一名健康的12岁男孩患KLA的病例。据我们所知,这是韩国首例报道的无基础疾病的免疫功能正常儿童患KLA的病例。该患者接受了经皮导管引流和抗生素治疗。导管置于肝内脓肿3周,静脉注射抗生素(头孢曲松和阿米卡星)4周,随后口服抗生素(头孢克肟)2周。我们报告此病例是为了提高医生对免疫功能正常儿童KLA的认识,并回顾KLA的诊断、危险因素、潜在并发症及适当治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfc2/3819678/05e03130141c/kjped-56-407-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfc2/3819678/05e03130141c/kjped-56-407-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfc2/3819678/05e03130141c/kjped-56-407-g001.jpg

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本文引用的文献

1
Complications of percutaneous fluid drainage.经皮液体引流的并发症。
Semin Intervent Radiol. 2006 Jun;23(2):194-204. doi: 10.1055/s-2006-941450.
2
Klebsiella pneumoniae liver abscess: an emerging problem in North America.肺炎克雷伯菌肝脓肿:北美地区一个新出现的问题。
J Emerg Med. 2011 Nov;41(5):e103-5. doi: 10.1016/j.jemermed.2008.04.041. Epub 2008 Nov 7.
3
Evidence for clonal dissemination of the serotype K1 Klebsiella pneumoniae strain causing invasive liver abscesses in Korea.韩国导致侵袭性肝脓肿的肺炎克雷伯菌K1血清型菌株克隆传播的证据。
革兰氏阴性细菌病原体的铁获取系统定义了依赖 TonB 的新型抗生素途径。
Chem Rev. 2021 May 12;121(9):5193-5239. doi: 10.1021/acs.chemrev.0c01005. Epub 2021 Mar 16.
4
Successful Use of Tissue Plasminogen Activator in an Adolescent Male with Pyogenic Liver Abscess.组织型纤溶酶原激活剂在一名患有化脓性肝脓肿的青少年男性中的成功应用。
Case Rep Crit Care. 2019 Apr 14;2019:5735312. doi: 10.1155/2019/5735312. eCollection 2019.
5
Structural and functional delineation of aerobactin biosynthesis in hypervirulent .超毒力 中 aerobactin 生物合成的结构和功能划分。
J Biol Chem. 2018 May 18;293(20):7841-7852. doi: 10.1074/jbc.RA118.002798. Epub 2018 Apr 4.
6
Hypervirulence and hypermucoviscosity: Two different but complementary Klebsiella spp. phenotypes?高毒力和高黏液性:两种不同但互补的克雷伯菌属表型?
Virulence. 2017 Oct 3;8(7):1111-1123. doi: 10.1080/21505594.2017.1317412. Epub 2017 Apr 12.
J Clin Microbiol. 2008 Dec;46(12):4061-3. doi: 10.1128/JCM.01577-08. Epub 2008 Oct 29.
4
Pyogenic liver abscess caused by Klebsiella pneumoniae: analysis of the clinical characteristics and outcomes of 84 patients.肺炎克雷伯菌所致肝脓肿:84例患者临床特征及结局分析
Chin Med J (Engl). 2007 Jan 20;120(2):136-9.
5
Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea.韩国出现的由肺炎克雷伯菌K1血清型引起的侵袭性肝脓肿
J Infect. 2007 Jun;54(6):578-83. doi: 10.1016/j.jinf.2006.11.008. Epub 2006 Dec 18.
6
Liver abscesses in children: a single center experience in the developed world.儿童肝脓肿:发达国家的单中心经验
J Pediatr Gastroenterol Nutr. 2006 Feb;42(2):201-6. doi: 10.1097/01.mpg.0000189344.23387.26.
7
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8
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Clin Infect Dis. 2004 Dec 1;39(11):1654-9. doi: 10.1086/425616. Epub 2004 Nov 9.
9
Population-based study of the epidemiology of and the risk factors for pyogenic liver abscess.基于人群的化脓性肝脓肿流行病学及危险因素研究。
Clin Gastroenterol Hepatol. 2004 Nov;2(11):1032-8. doi: 10.1016/s1542-3565(04)00459-8.
10
Clinicopathological analysis of liver abscess in Japan.日本肝脓肿的临床病理分析
Int J Mol Med. 2002 Nov;10(5):627-30.