Lakke E A, Guldemond J M, Voogd J
Acta Histochem Suppl. 1986;32:47-51.
This study investigates the ontogeny of the spinocerebellar projection and especially focuses on the relation between temporary longitudinal patterns in the cytoarchitecture of the developing cerebellum of the chicken and the emergence of longitudinal patterning in the spinocerebellar projection, WGA-HRP was injected into the spinal cord of chicken embryos at different stages of development. It was found that spinocerebellar fibers arrive in the cerebellar "anlage" before any longitudinal cytoarchitectonic pattern can be discerned. Thereafter the organization of the spinocerebellar projection seems to develop related to the two temporary cytoarchitectonic longitudinal patterns present in the chick cerebellum. In both stages the development of the spinocerebellar projection displays a rostro-caudal gradient.
本研究调查了脊髓小脑投射的个体发生，尤其关注鸡发育中小脑细胞结构的暂时纵向模式与脊髓小脑投射中纵向模式出现之间的关系。将WGA-HRP注入不同发育阶段鸡胚的脊髓。结果发现，脊髓小脑纤维在任何纵向细胞结构模式可辨别之前就到达小脑“原基”。此后，脊髓小脑投射的组织似乎与鸡小脑中存在的两种暂时细胞结构纵向模式相关地发展。在两个阶段中，脊髓小脑投射的发育均显示出由头向尾的梯度。
