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一种罕见耳鼻喉肿瘤的突发临床病程:多发性骨髓瘤继发髓外浆细胞瘤的临床症状

Sudden clinical course of an unusual ENT tumour: clinical pictures of extramedullary plasmacytoma secondary to multiple myeloma.

作者信息

Pagella F, Canzi P, Matti E, Benazzo M

机构信息

Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico "S. Matteo" Foundation, Pavia, Italy.

出版信息

Acta Otorhinolaryngol Ital. 2013 Oct;33(5):347-9.

PMID:24227902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3825039/
Abstract

Extramedullary plasmacytoma (EMP) is a rare monoclonal plasmacytic proliferation involving upper airways in 80% of cases. The heterogeneous pattern of frequency in the head and neck area may result in insidious clinical expressions that are potentially lethal for the patient. The presentation and management of two suggestive clinical photographs characterized by sudden and aggressive EMP development secondary to multiple myeloma are discussed.

摘要

髓外浆细胞瘤(EMP)是一种罕见的单克隆浆细胞增殖性疾病,80%的病例累及上呼吸道。头颈部区域频率的异质性模式可能导致隐匿的临床症状,对患者具有潜在致命性。本文讨论了两张具有提示性的临床照片,其特征为继发于多发性骨髓瘤的突然且侵袭性的EMP发展情况及处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/54fdc09ca895/0392-100X-33-347-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/cd12a0500bc7/0392-100X-33-347-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/fb521ecee358/0392-100X-33-347-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/54fdc09ca895/0392-100X-33-347-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/cd12a0500bc7/0392-100X-33-347-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/fb521ecee358/0392-100X-33-347-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ae/3825039/54fdc09ca895/0392-100X-33-347-g003.jpg

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Sudden clinical course of an unusual ENT tumour: clinical pictures of extramedullary plasmacytoma secondary to multiple myeloma.一种罕见耳鼻喉肿瘤的突发临床病程:多发性骨髓瘤继发髓外浆细胞瘤的临床症状
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本文引用的文献

1
Multiple myeloma with extramedullary disease.多发性骨髓瘤伴髓外疾病。
Adv Ther. 2011 Nov;28 Suppl 7:1-6. doi: 10.1007/s12325-011-0079-0. Epub 2011 Nov 11.
2
Endoscopic endonasal transsphenoidal resection of solitary extramedullary plasmacytoma in the sphenoid sinus with destruction of skull base.经鼻内镜经蝶窦入路切除蝶窦内孤立性髓外浆细胞瘤并累及颅底骨质破坏
J Korean Neurosurg Soc. 2009 Aug;46(2):156-60. doi: 10.3340/jkns.2009.46.2.156. Epub 2009 Aug 31.
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Am J Otolaryngol. 2007 Jan-Feb;28(1):50-1. doi: 10.1016/j.amjoto.2005.09.017.
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Extramedullary plasmacytoma of paranasal sinuses. A combined therapeutic strategy.鼻窦髓外浆细胞瘤。一种联合治疗策略。
Acta Otorhinolaryngol Ital. 2006 Apr;26(2):118-20; discussion 120.
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Plasmacytoma and upper airway obstruction.浆细胞瘤与上呼吸道梗阻。
Am J Otolaryngol. 1999 Jul-Aug;20(4):257-9. doi: 10.1016/s0196-0709(99)90011-x.
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Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts.髓外浆细胞瘤:肿瘤发生与治疗理念
Cancer. 1999 Jun 1;85(11):2305-14.
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[Plasmacytomas of the head and neck].[头颈部浆细胞瘤]
Acta Otorhinolaryngol Ital. 1996 Feb;16(1):6-15.
10
[Extramedullary plasmocytoma (EMP) of the head and neck: a series of 22 cases].[头颈部髓外浆细胞瘤(EMP):22例病例系列]
Acta Otorhinolaryngol Ital. 1995 Dec;15(6):437-42.