Jurdy Lama, Merks Johanus H M, Pieters Bradly R, Mourits Maarten P, Kloos Roel J H M, Strackee Simone D, Saeed Peerooz
Orbital Centre, Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Saudi J Ophthalmol. 2013 Jul;27(3):167-75. doi: 10.1016/j.sjopt.2013.06.004.
Rhabdomyosarcoma (RMS) is a highly malignant tumor and is one of the few life-threatening diseases that present first to the ophthalmologist. It is the most common soft-tissue sarcoma of the head and neck in childhood with 10% of all cases occurring in the orbit. RMS has been reported from birth to the seventh decade, with the majority of cases presenting in early childhood. Survival has changed drastically over the years, from 30% in the 1960's to 90% presently, with the advent of new diagnostic and therapeutic modalities. The purpose of this review is to provide a general overview of primary orbital RMS derived from a literature search of material published over the last 10 years, as well as to present two representative cases of patients that have been managed at our institute.
横纹肌肉瘤（RMS）是一种高度恶性肿瘤，是少数首先就诊于眼科医生的危及生命的疾病之一。它是儿童期头颈部最常见的软组织肉瘤，10%的病例发生在眼眶。RMS从出生到七十岁均有报道，大多数病例出现在幼儿期。多年来，随着新的诊断和治疗方式的出现，生存率发生了巨大变化，从20世纪60年代的30%提高到目前的90%。本综述的目的是通过对过去10年发表的文献资料进行检索，对原发性眼眶RMS进行概述，并介绍在我们研究所接受治疗的两名代表性患者病例。
