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[免疫1联合高效抗逆转录病毒治疗对HIV/AIDS患者免疫功能重建的干预]

[Intervention of immune 1 combined HAART on immune function in patients with HIV/AIDS reconstruction].

作者信息

Wu Xin-Fang, Wang Jie, Li Yong

机构信息

Guang'anmen Hospital of China Academy of Traditional Chinese Medicine, Beijing 100053, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2013 Aug;38(15):2453-7.

PMID:24228534
Abstract

OBJECTIVE

To observe the effect of combination of Immune 1 and HAART on the CD4+ T cell count and its immune reconstitution rate.

METHOD

Two hundred and twenty eight HIV/AIDS patients were randomly divided into treatment group and control group, patients from treatment group received Immune 1 combined HAART therapy, patients from control group was given placebo combined HAART and evaluate the change of CD4+ T cell count and its immune reconstitution rate.

RESULT

In patients with CD4+ T cells baseline level (200-350 cell x microL(-1)), Immune reconstitution rate of treatment group is significantly higher than the control group.

CONCLUSION

Immune 1 combined HAART can effectively promote the immune reconstitution of patients with high CD4+ T cells baseline level(200-350 cell x microL(-1)) and show little side effect and is safe to treat HIV/AIDS disease.

摘要

目的

观察免疫1号联合高效抗逆转录病毒疗法(HAART)对CD4+T细胞计数及其免疫重建率的影响。

方法

将228例HIV/AIDS患者随机分为治疗组和对照组,治疗组患者接受免疫1号联合HAART治疗,对照组患者给予安慰剂联合HAART,评估CD4+T细胞计数的变化及其免疫重建率。

结果

在CD4+T细胞基线水平为(200 - 350个/微升)的患者中,治疗组的免疫重建率显著高于对照组。

结论

免疫1号联合HAART能有效促进CD4+T细胞基线水平较高(200 - 350个/微升)患者的免疫重建,且副作用小,治疗HIV/AIDS疾病安全。

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