LifeSciences Press, Washington, DC.
World Allergy Organ J. 2009 Aug 15;2(8):155. doi: 10.1186/1939-4551-2-8-155.
"Nonallergic vasomotor rhinitis" (also referred to as nonallergic rhinitis and/or idiopathic rhinitis) is a term that has been used to describe a common nasal condition of unclear pathophysiology. Clinical options for patients are limited by a lack of straight-forward diagnostic criteria and poorly defined and heterogeneous populations in clinical trials. A roundtable conference convened in December 2008 addressed these challenges. Part 1 of the proceedings of that meeting provided a consensus definition of "nonallergic rhinopathy," proposed to replace the former terms above based on the clinical characteristics of the disease, which were described in individual papers. Part 2 of the proceedings uses the revised definition for a consensus discussion on appropriate criteria for enrolling subjects in future clinical studies of the efficacy of potential treatments for this disease.
“非变应性血管运动性鼻炎”(也称为非变应性鼻炎和/或特发性鼻炎)是一个用来描述一种常见的鼻腔疾病的术语,其发病机制尚不清楚。由于缺乏直接的诊断标准,以及临床试验中人群定义不明确且存在异质性,患者的临床选择受到限制。2008 年 12 月召开了一次圆桌会议,以应对这些挑战。会议的第一部分提供了“非变应性鼻病”的共识定义,建议用该定义取代上述旧术语,其依据是疾病的临床特征,这些特征在各个论文中均有描述。会议第二部分使用修订后的定义,就未来对该疾病潜在治疗方法的疗效进行临床研究时应纳入受试者的适当标准进行了共识讨论。