From the Institute for Asthma and Allergy, Chevy Chase, Md, and George Washington University School of Medicine, Washington, DC.
World Allergy Organ J. 2009 Jun 15;2(6):98-101. doi: 10.1097/WOX.0b013e3181a9d55b.
Many patients have nasal syndromes that are nonallergic and noninfectious and not caused by mechanical or anatomic abnormalities. There are at least 8 recognized nonallergic rhinitis syndromes: drug-induced rhinitis including rhinitis medicamentosa, gustatory rhinitis, hormonally induced rhinitis including the rhinitis of pregnancy, nonallergic rhinitis with eosinophilia syndrome, senile rhinitis, atrophic rhinitis, cerebral spinal fluid leak, and vasomotor rhinitis. Few studies have explored etiologic causes. These syndromes are distinguished by clinical characteristics, recognized triggering conditions, and concomitant observations such as nasal eosinophilia or cerebral spinal fluid leak. Until more specific subjective clinical characteristics and/or objective measures can better define and differentiate underlying causes for these disparate diseases, they will remain a murky group of overlapping syndromes.
许多患者有非变应性和非传染性的鼻部综合征,也不是由机械或解剖异常引起的。至少有 8 种公认的非变应性鼻炎综合征:药物性鼻炎,包括药物性鼻炎、味觉性鼻炎、激素引起的鼻炎,包括妊娠性鼻炎、伴有嗜酸性粒细胞增多的非变应性鼻炎、老年性鼻炎、萎缩性鼻炎、脑脊液漏和血管舒缩性鼻炎。很少有研究探讨其病因。这些综合征的区别在于临床特征、公认的诱发条件以及伴随的观察结果,如鼻嗜酸粒细胞增多或脑脊液漏。在能够更好地定义和区分这些不同疾病的潜在病因的更具体的主观临床特征和/或客观措施出现之前,它们将仍然是一组模糊的重叠综合征。