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老年期抑郁症的病因有哪些?

What are the causes of late-life depression?

机构信息

Department of Psychiatry, Institute of Living, Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA; Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA; Department of Psychiatry, University of Connecticut Health Center, Building L, MC 1410, 263 Farmington Avenue, Farmington, CT 06030, USA.

出版信息

Psychiatr Clin North Am. 2013 Dec;36(4):497-516. doi: 10.1016/j.psc.2013.08.001. Epub 2013 Oct 6.

DOI:10.1016/j.psc.2013.08.001
PMID:24229653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4084923/
Abstract

Although depression in old age is less common than depression in younger populations, it still affects more than 1 million community-living older adults. Depression in late life has been associated with reduced quality of life and increased mortality from both suicide and illness. Its causes are multifactorial but are prominently related to both biologic and social factors. Psychological factors, although less studied in elders, are also important in understanding its cause. In this article, multiple facets of late-life depression are reviewed, including its clinical presentation, epidemiology, and biopsychosocial causes.

摘要

尽管老年人的抑郁症比年轻人少见,但它仍然影响着超过 100 万的社区居住的老年人。老年期抑郁症与生活质量降低以及自杀和疾病导致的死亡率增加有关。其病因是多因素的,但主要与生物和社会因素有关。尽管在老年人中研究较少,但心理因素对于理解其病因也很重要。本文回顾了老年期抑郁症的多个方面,包括其临床表现、流行病学和生物心理社会病因。

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本文引用的文献

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A systematic review and meta-analysis of magnetic resonance imaging studies in late-life depression.一项关于老年期抑郁症的磁共振成像研究的系统回顾和荟萃分析。
Am J Geriatr Psychiatry. 2013 Feb;21(2):184-95. doi: 10.1016/j.jagp.2012.10.019. Epub 2013 Jan 22.
2
The prevalence of mental disorders in older people in Western countries - a meta-analysis.西方国家老年人精神障碍的患病率——一项荟萃分析。
Ageing Res Rev. 2013 Jan;12(1):339-53. doi: 10.1016/j.arr.2012.09.004. Epub 2012 Sep 19.
3
Incidence of late-life depression: a systematic review.老年期抑郁症的发病率:一项系统综述。
J Affect Disord. 2012 Dec 15;142(1-3):172-9. doi: 10.1016/j.jad.2012.05.010. Epub 2012 Aug 30.
4
Biopsychosocial factors related to depression in aged care residents.与老年护理居民抑郁相关的生物心理社会因素。
J Affect Disord. 2012 Dec 15;142(1-3):290-6. doi: 10.1016/j.jad.2012.05.019. Epub 2012 Aug 17.
5
Depression as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies.抑郁作为痴呆和轻度认知障碍的风险因素:纵向研究的荟萃分析。
Int J Geriatr Psychiatry. 2013 May;28(5):441-9. doi: 10.1002/gps.3845. Epub 2012 Jul 19.
6
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N Engl J Med. 2012 Aug 30;367(9):795-804. doi: 10.1056/NEJMoa1202753. Epub 2012 Jul 11.
8
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