Department of Mechanical Engineering, Indian Institute of Technology Guwahati, Guwahati 781039, India.
J Therm Biol. 2013 Jan;38(1):32-40. doi: 10.1016/j.jtherbio.2012.10.003. Epub 2012 Oct 26.
This article deals with the numerical analysis to ascertain the presence of a tumor and to estimate its size and location in a tissue. Heat transfer in the tissue is modeled using the Pennes bioheat transfer equation, and is solved using the finite volume method. Consideration is given to 1-D brain and breast tissues. Temperature distributions in the tissues are specific to the tumor grades, its locations and sizes, and these are different than that of a normal tissue. With temperature distribution known a priori, estimations of the position and the size of a tumor are done using the inverse analysis. The proposed approach gives a correct estimation of the presence of a tumor and its location and size.
本文涉及数值分析以确定肿瘤的存在，并估计其在组织中的大小和位置。使用彭内斯生物传热方程对组织中的热传递进行建模，并使用有限体积法求解。考虑一维脑和乳腺组织。组织中的温度分布与肿瘤等级、位置和大小有关，与正常组织不同。在预先知道温度分布的情况下，使用逆分析来估计肿瘤的位置和大小。所提出的方法可以正确估计肿瘤的存在及其位置和大小。
