通过亲和相分配研究聚乙二醇结合脂肪酸与人血清白蛋白和甲胎蛋白结合的比较。
Comparison of the binding of poly(ethylene glycol)-bound fatty acids to human albumin and alpha-fetoprotein studied by affinity phase partitioning.
作者信息
Birkenmeier G, Shanbhag V P, Kopperschläger G
出版信息
Biomed Biochim Acta. 1986;45(3):285-9.
The interaction of human serum albumin and of alpha-fetoprotein to poly(ethylene glycol)-bound fatty acids is compared using the method of affinity partitioning in an aqueous two-phase system composed of dextran, poly(ethylene glycol) and esters of different fatty acids with poly(ethylene glycol). Albumin was found to be bound to the fatty acid derivatives with higher affinity than alpha-fetoprotein. For both proteins binding occurred in dependence on the chain length of the fatty acids with a maximum for the C14-derivative.
采用亲和分配法，在由葡聚糖、聚乙二醇以及不同脂肪酸与聚乙二醇的酯组成的水两相系统中，比较了人血清白蛋白和甲胎蛋白与聚乙二醇结合脂肪酸的相互作用。结果发现，白蛋白与脂肪酸衍生物的结合亲和力高于甲胎蛋白。对于这两种蛋白质，结合作用均取决于脂肪酸的链长，其中C14衍生物的结合作用最强。
Zotero 插件