Pineiro A, Olivito A M, Uriel J
C R Seances Acad Sci D. 1979 Nov 26;289(14):1053-6.
Quantitative data are presented on the fatty acid composition of rat alpha-fetoprotein (AFP) and serum albumin, (SA), and of brain extracts of suckling rats. In AFP and SA preparations, 40% and 13%, respectively, of total fatty acids present are polyenoic acids. Among them, docosahexaenoic acid is quantitatively the most important in AFP, while in SA, arachidonic acid is largely predominant. Both docosahexaenoic and arachidonic acids were the predominant polyenoic acids in brain extracts. The rate of accumulation of these acids in the brain of suckling rats and the rate of AFP secretion during the same period showed a maximum around 10--12 days after birth. These results suggest that AFP and SA play an important role in the transport and the incorporation of polyunsaturated fatty acids in the developing brain.
给出了关于大鼠甲胎蛋白（AFP）、血清白蛋白（SA）以及乳鼠脑提取物脂肪酸组成的定量数据。在AFP和SA制剂中，所存在的总脂肪酸分别有40%和13%是多烯酸。其中，二十二碳六烯酸在AFP中在数量上最为重要，而在SA中，花生四烯酸占主导地位。二十二碳六烯酸和花生四烯酸都是脑提取物中的主要多烯酸。这些酸在乳鼠脑中的积累速率以及同期AFP的分泌速率在出生后约10 - 12天达到最大值。这些结果表明，AFP和SA在发育中的大脑中多不饱和脂肪酸的运输和掺入过程中发挥着重要作用。
