Lee J A
Exp Cell Biol. 1986;54(2):89-93. doi: 10.1159/000163348.
Neutrophil polymorphonuclear leucocytes contain a special electron transport chain which is involved in the killing of bacteria in these cells. Identified components of the chain include NADPH, a flavoprotein dehydrogenase and an unusual cytochrome b, but there has been recent disagreement in the biochemical literature as to whether or not an ubiquinone is also present. This study has looked at this question by using an independent histochemical technique for ubiquinones. The results indicate that an ubiquinone is found in association with neutrophil granules, and hence may be implicated in the radical generating system.
中性粒细胞含有一种特殊的电子传递链，该链参与这些细胞内细菌的杀灭过程。已确定的该链组成成分包括还原型辅酶Ⅱ、一种黄素蛋白脱氢酶和一种特殊的细胞色素b，但最近生物化学文献中对于是否也存在泛醌存在分歧。本研究通过使用一种独立的泛醌组织化学技术来研究这个问题。结果表明，在中性粒细胞颗粒中发现了泛醌，因此它可能与自由基生成系统有关。
