School of Biological Sciences, University of Sydney, Sydney, NSW 2006, Australia.
Bioinformatics. 2014 Apr 1;30(7):1017-9. doi: 10.1093/bioinformatics/btt665. Epub 2013 Nov 14.
Relaxed molecular clocks allow the phylogenetic estimation of evolutionary timescales even when substitution rates vary among branches. In analyses of large multigene datasets, it is often appropriate to use multiple relaxed-clock models to accommodate differing patterns of rate variation among genes. We present ClockstaR, a method for selecting the number of relaxed clocks for multigene datasets.
ClockstaR is freely available for download at http://sydney.edu.au/science/biology/meep/software/.
松弛分子钟允许在替换率在分支之间变化的情况下对进化时间尺度进行系统发育估计。在分析大型多基因数据集时，通常需要使用多个松弛时钟模型来适应基因之间不同的速率变化模式。我们提出了 ClockstaR，这是一种用于选择多基因数据集的松弛时钟数量的方法。
ClockstaR 可在 http://sydney.edu.au/science/biology/meep/software/ 免费下载。
