Institut de Technologie des Surfaces Actives, Université de Compiègne, BP. 233, 60206, Compiegne, France.
Appl Biochem Biotechnol. 1982 Nov;7(6):459-62. doi: 10.1007/BF02799177.
Anti-Major Cathodic Antigen (MCA) monospecific immunoglobulins ofT. cruzi have been used for the preparation of polyamide-linked immunoadsorbents. A high proportion of serologically positive patients with Chagas disease show the presence of a soluble antigen complexed with human immunoglobulins, which complex binds to those immunoadsorbents as determined by a double sandwich reaction and a peroxidase final determination.
抗 T. cruzi 主要细胞表面抗原(MCA)单克隆免疫球蛋白已被用于制备聚酰胺连接免疫吸附剂。在恰加斯病的血清学阳性患者中,很大一部分存在与人类免疫球蛋白结合的可溶性抗原复合物,该复合物通过双夹心反应和过氧化物酶最终测定确定与那些免疫吸附剂结合。