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本文引用的文献

1
Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes.骨髓衰竭患者的单核苷酸多态性微阵列分析揭示了特征性的遗传变化模式。
Br J Haematol. 2014 Jan;164(1):73-82. doi: 10.1111/bjh.12603. Epub 2013 Oct 14.
2
Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients.常见的谷胱甘肽 S-转移酶 theta 多态性缺失易导致获得性再生障碍性贫血：609 例患者的独立队列和荟萃分析。
Am J Hematol. 2013 Oct;88(10):862-7. doi: 10.1002/ajh.23521. Epub 2013 Jul 23.
3
Safety and efficacy of iron chelation therapy with deferiprone in patients with transfusion-dependent thalassemia.去铁酮治疗输血依赖型地中海贫血患者的安全性和有效性。
Ther Adv Hematol. 2012 Oct;3(5):299-307. doi: 10.1177/2040620712450252.
4
The optimal immunosuppressive therapy for aplastic anemia.再生障碍性贫血的最佳免疫抑制治疗。
Int J Hematol. 2013 May;97(5):564-72. doi: 10.1007/s12185-013-1331-y. Epub 2013 Apr 19.
5
Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia.一名获得性重度再生障碍性贫血儿童成功进行自体脐带血移植。
Pediatr Transplant. 2013 May;17(3):E104-7. doi: 10.1111/petr.12068. Epub 2013 Mar 7.
6
Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematological malignancies and solid tumors : guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).血液系统恶性肿瘤和实体瘤患者细菌感染和卡氏肺孢子菌肺炎的一级预防：德国血液学和肿瘤学会感染病工作组（AGIHO）指南。
Ann Hematol. 2013 Apr;92(4):433-42. doi: 10.1007/s00277-013-1698-0. Epub 2013 Feb 15.
7
Excellent outcome of haploidentical hematopoietic stem cell transplantation in children and adolescents with acquired severe aplastic anemia.同种异体造血干细胞移植治疗获得性重型再生障碍性贫血患儿和青少年的良好结果。
Biol Blood Marrow Transplant. 2013 May;19(5):754-9. doi: 10.1016/j.bbmt.2013.01.023. Epub 2013 Feb 1.
8
Comparison of the efficacy of rabbit and horse antithymocyte globulin for the treatment of severe aplastic anemia in children.兔抗胸腺细胞球蛋白与马抗胸腺细胞球蛋白治疗儿童重型再生障碍性贫血的疗效比较。
Blood. 2013 Jan 31;121(5):860-1. doi: 10.1182/blood-2012-10-461509.
9
Unrelated donor search and unrelated donor transplantation in the adult aplastic anaemia patient aged 18-40 years without an HLA-identical sibling and failing immunosuppression.18-40 岁、无 HLA 完全相合同胞供者且免疫抑制治疗失败的成人再生障碍性贫血患者的无关供者搜索和无关供者移植。
Bone Marrow Transplant. 2013 Feb;48(2):198-200. doi: 10.1038/bmt.2012.233. Epub 2012 Nov 26.
10
Front-line immunosuppressive treatment of acquired aplastic anemia.获得性再生障碍性贫血的一线免疫抑制治疗。
Bone Marrow Transplant. 2013 Feb;48(2):174-7. doi: 10.1038/bmt.2012.222. Epub 2012 Nov 19.

儿童获得性再生障碍性贫血。

Acquired aplastic anemia in children.

机构信息

Division of Hematology, Department of Pediatrics, Comprehensive Bone Marrow Failure Center, The Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, ARC 302, Philadelphia, PA 19104, USA.

出版信息

Pediatr Clin North Am. 2013 Dec;60(6):1311-36. doi: 10.1016/j.pcl.2013.08.011. Epub 2013 Oct 16.

DOI:10.1016/j.pcl.2013.08.011
PMID:24237973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3894991/
Abstract

This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder.

摘要

本文提供了一种基于实践和简洁的儿童获得性再生障碍性贫血的病因、诊断和管理综述。骨髓移植、免疫抑制疗法和支持性治疗都进行了详细讨论。目的是使临床医生更好地了解这种疾病，并为治疗这种罕见但严重的疾病提供指导。