Flaherty Amber, Kim Timothy, Giuliano Anna, Magliocco Anthony, Hakky Tariq S, Pagliaro Lance C, Spiess Philippe E
Department of Hematology Oncology, University of South Florida, Tampa, FL.
Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL.
Urol Oncol. 2014 Jan;32(1):53.e1-8. doi: 10.1016/j.urolonc.2013.08.010. Epub 2013 Nov 13.
Human papillomavirus infection (HPV) has been implicated in penile cancer, and although the annual incidence is estimated to be 1,570 in the United States, there are areas of the world in which the incidence is as much as 20-fold higher. Ample data in the literature support testing and vaccination against HPV-related cervical cancer, but for men and penile cancer, these data are lacking. However, some preliminary data would suggest that HPV not only plays an important role in a significant subset of patients with penile cancer but also may be a target for penile cancer prevention as well via initiation of a vaccination program in high-risk male populations.
人乳头瘤病毒感染（HPV）与阴茎癌有关，尽管在美国阴茎癌的年发病率估计为1570例，但在世界上一些地区，其发病率高达20倍之多。文献中有大量数据支持针对HPV相关宫颈癌的检测和疫苗接种，但对于男性和阴茎癌，这些数据却很缺乏。然而，一些初步数据表明，HPV不仅在相当一部分阴茎癌患者中起重要作用，而且通过在高危男性人群中启动疫苗接种计划，也可能成为阴茎癌预防的一个靶点。
