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三级医疗中心结直肠癌梗阻支架置入术的临床结果

Clinical outcomes of stenting for colorectal obstruction at a tertiary centre.

作者信息

Alford Tyler, Ghosh Sunita, Wong Clarence, Schiller Daniel

机构信息

Division of General Surgery, University of Alberta, 2D2.08 WMC University of Alberta Hospital 8440 - 112 Street, Edmonton, AB, T6G 2B7, Canada,

出版信息

J Gastrointest Cancer. 2014 Mar;45(1):61-5. doi: 10.1007/s12029-013-9557-8.

Abstract

PURPOSE

Self-expandable metal stents (SEMS) have been used to manage large bowel obstruction as a palliative treatment or to initially decompress the colon as a bridge to definitive surgery. Our goal was to review clinical outcomes in patients undergoing placement of a SEMS for colorectal obstruction at a tertiary care hospital.

METHODS

A retrospective review was done of patients undergoing placement of a colorectal SEMS at a single centre between August 2005 and March 2011 for obstructing lesions. Outcomes identified included clinical relief of obstruction, successful bridging to surgery or palliation, and stent-related complications.

RESULTS

SEMS were placed in a total of 58 patients. The intent of stenting was to bridge to definitive surgery in 11 patients and palliation in 47 patients. Stent placement was clinically successful in relieving obstruction without early complication in 45 (78%) patients. Of the patients intended to bridge to surgery, 7/11 (64%) were successfully bridged to surgery. One patient suffered a perforation, two failed to relieve obstruction, and one re-obstructed. Of the patients stented for palliation, 32/47 (68%) were successfully palliated at a mean follow-up of 7.5 months. Five patients had perforations, six re-obstructed, two had stent migration, and two failed to relieve obstruction. The overall rates for perforation, re-obstruction, and stent migration were 10, 12, and 7%, respectively.

CONCLUSION

SEMS placement as a bridge to surgery and for palliation of colorectal obstruction is associated with moderate rates of clinical success but a high rate of perforation.

摘要

目的

自膨式金属支架(SEMS)已被用于治疗大肠梗阻,作为一种姑息治疗手段,或在进行确定性手术前作为结肠减压的初始措施。我们的目标是回顾在一家三级医院接受SEMS置入术治疗大肠梗阻患者的临床结局。

方法

对2005年8月至2011年3月期间在单一中心因梗阻性病变接受大肠SEMS置入术的患者进行回顾性研究。确定的结局包括梗阻的临床缓解、成功过渡到手术或姑息治疗以及与支架相关的并发症。

结果

共有58例患者置入了SEMS。置入支架的目的是11例患者过渡到确定性手术,47例患者进行姑息治疗。45例(78%)患者支架置入在临床上成功缓解了梗阻且无早期并发症。在计划过渡到手术的患者中,7/11(64%)成功过渡到了手术。1例患者发生穿孔,2例未能缓解梗阻,1例再次梗阻。在接受姑息治疗的支架置入患者中,32/47(68%)在平均7.5个月的随访中成功得到姑息治疗。5例患者发生穿孔,6例再次梗阻,2例支架移位,2例未能缓解梗阻。穿孔、再次梗阻和支架移位的总体发生率分别为10%、12%和7%。

结论

SEMS置入作为手术过渡和大肠梗阻姑息治疗手段,临床成功率中等,但穿孔发生率较高。

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