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结直肠支架置入术在急性恶性大肠梗阻中的应用:新加坡一家三级转诊中心的疗效和安全性评估。

Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre.

机构信息

Department of Gastroenterology and Hepatology, Changi General Hospital, Singapore Health Services, Singapore.

Department of General Surgery, Changi General Hospital, Singapore Health Services, Singapore.

出版信息

Singapore Med J. 2023 Oct;64(10):603-608. doi: 10.11622/smedj.2021127.

Abstract

INTRODUCTION

Acute malignant large bowel obstruction (MBO) occurs in 8%-15% of colorectal cancer patients. Self-expandable metal stents (SEMS) have progressed from a palliative modality to use as bridge to surgery (BTS). We aimed to assess the safety and efficacy of SEMS for MBO in our institution.

METHODS

The data of patients undergoing SEMS insertion for MBO were reviewed. Technical success was defined as successful SEMS deployment across tumour without complications. Clinical success was defined as colonic decompression without requiring further surgical intervention. Rates of complications, median time to surgery, types of surgery and rates of recurrence were studied.

RESULTS

Seventy-nine patients underwent emergent SEMS placement from September 2013 to February 2020. Their mean age was 68.8 ± 13.8 years and 43 (54%) patients were male. Mean tumour length was 4.2 cm ± 2.2 cm; 89.9% of malignant strictures were located distal to the splenic flexure. Technical and clinical success was 94.9% and 98.7%, respectively. Perforation occurred in 5.1% of patients, with none having stent migration or bleeding. Fifty (63.3%) patients underwent SEMS insertion as BTS. Median time to surgery was 20 (range 6-57) days. Most (82%) patients underwent minimally invasive surgery. Primary anastomosis rate was 98%. Thirty-nine patients had follow-up beyond 1-year posttreatment (median 34 months). Local recurrence and distant metastasis were observed in 4 (10.3%) and 5 (12.8%) patients, respectively.

CONCLUSION

Insertion of SEMS for acute MBO has high success rates and a good safety profile. Most patients in this audit underwent minimally invasive surgery and primary anastomosis after successful BTS.

摘要

简介

急性恶性大肠梗阻(MBO)在 8%-15%的结直肠癌患者中发生。自膨式金属支架(SEMS)已从姑息治疗方式发展为桥接手术(BTS)。我们旨在评估 SEMS 在我们机构中用于 MBO 的安全性和疗效。

方法

回顾了因 MBO 行 SEMS 置入术的患者数据。技术成功定义为支架成功穿过肿瘤而无并发症。临床成功定义为结肠减压而无需进一步手术干预。研究了并发症发生率、中位手术时间、手术类型和复发率。

结果

2013 年 9 月至 2020 年 2 月,79 例患者行紧急 SEMS 置入术。患者的平均年龄为 68.8±13.8 岁,43 例(54%)为男性。平均肿瘤长度为 4.2±2.2cm;89.9%的恶性狭窄位于脾曲以下。技术和临床成功率分别为 94.9%和 98.7%。穿孔发生率为 5.1%,无支架移位或出血。50 例(63.3%)患者行 SEMS 置入作为 BTS。中位手术时间为 20(6-57)天。大多数(82%)患者行微创手术。一期吻合率为 98%。39 例患者在治疗后 1 年以上进行了随访(中位随访时间为 34 个月)。4 例(10.3%)患者出现局部复发,5 例(12.8%)患者出现远处转移。

结论

SEMS 置入治疗急性 MBO 成功率高,安全性好。本研究中大多数患者在成功 BTS 后行微创和一期吻合术。

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