Tate David, Cairnes Vida, Valori Roland, Makins Richard
Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, United Kingdom.
J Clin Apher. 2014 Jun;29(3):181-2. doi: 10.1002/jca.21308. Epub 2013 Nov 18.
We describe the case of a 24 year old male with severe fistulating Crohn's disease who failed mutliple modalities of medical and surgical therapy. We present objective and subjective evidence of disease remission after induction and maintenance treatment with leukocyte apheresis. This is the first described case of successful maintenance treatment of severe Crohn's disease with leukocyte apheresis in the United Kingdom.
我们描述了一名患有严重瘘管性克罗恩病的24岁男性病例,该患者多种药物和手术治疗方式均告失败。我们展示了白细胞去除术诱导和维持治疗后疾病缓解的客观和主观证据。这是英国首例关于白细胞去除术成功维持治疗严重克罗恩病的病例报道。