Booth Helen P, Prevost A Toby, Gulliford Martin C
Pharmacoepidemiol Drug Saf. 2013 Dec;22(12):1357-61. doi: 10.1002/pds.3537.
Primary care electronic health records (EHRs) are increasingly used as a resource for epidemiological research. Cigarette smoking is an important variable in many epidemiological studies. We evaluated the validity of smoking records in primary care EHRs by comparing estimates for smoking prevalence from primary care EHRs with national health survey data.
Data were analysed for adults over 30 years of age from the Clinical Practice Research Datalink (CPRD) in comparison with data from the Health Survey for England between 2007 and 2011. Electronic health records in the CPRD were searched for records of smoking status and smoking cessation treatment. Annual age- and sex-standardised prevalence of current-, non- and former smoking were calculated, and compared with equivalent data from the Health Survey for England (HSE).
The difference between estimates of current smoking in CPRD and HSE was generally <1% from 2007 to 2011. In 2011, the prevalence of current smoking in men was: CPRD 24.3%, HSE 24.2%. The mean difference was 0.1% (95% confidence interval −1.5 to 1.7%). In women, current smoking prevalence was CPRD 20.3%, HSE 19.0%; mean difference 1.3% (0.0 to 2.6%). Estimates for former smoking were lower in CPRD than HSE for men (CPRD 26.7%, HSE 31.3%) and women (CPRD 22.9%, HSE 25.0%).
Prevalence estimates for current smoking, and non-smoking, from primary care EHRs are similar to those from nationally representative surveys, but former smoking may be under-recorded.
基层医疗电子健康记录(EHRs)越来越多地被用作流行病学研究的资源。吸烟是许多流行病学研究中的一个重要变量。我们通过比较基层医疗EHRs中的吸烟流行率估计值与全国健康调查数据,评估了基层医疗EHRs中吸烟记录的有效性。
分析了临床实践研究数据链(CPRD)中30岁以上成年人的数据,并与2007年至2011年英格兰健康调查的数据进行了比较。在CPRD的电子健康记录中搜索吸烟状况和戒烟治疗的记录。计算了当前、非吸烟和曾经吸烟的年度年龄和性别标准化流行率,并与英格兰健康调查(HSE)的等效数据进行了比较。
2007年至2011年,CPRD和HSE中当前吸烟估计值的差异一般<1%。2011年,男性当前吸烟流行率为:CPRD 24.3%,HSE 24.2%。平均差异为0.1%(95%置信区间-1.5至1.7%)。在女性中,当前吸烟流行率为CPRD 20.3%,HSE 19.0%;平均差异为1.3%(0.0至2.6%)。CPRD中曾经吸烟的估计值低于HSE中的男性(CPRD 26.7%,HSE 31.3%)和女性(CPRD 22.9%,HSE 25.0%)。
基层医疗EHRs中当前吸烟和非吸烟的流行率估计值与全国代表性调查的估计值相似,但曾经吸烟可能记录不足。