Mazzilli M C, Tanigaki N, Cascino I, Costanzi Porrini S, Trabace S, Cappellacci S, Testa L, Gandini E
Hum Immunol. 1986 Jun;16(2):148-56. doi: 10.1016/0198-8859(86)90043-1.
The hybridoma technique was used to produce a mouse monoclonal antibody, designated as XI 21.4, which belongs to the IgG2a class. It is active in complement-dependent cytotoxicity and detects a B-cell antigenic determinant associated with DR1, DR4, DRw10, and, possibly, DRw9. Microfingerprinting of the immunoprecipitate from a homozygous DR4 cell line shows a typical alpha DR pattern and a beta pattern coinciding with that of DR4 molecules.
