Snoeks T J A, van Driel P B A A, Keereweer S, Aime S, Brindle K M, van Dam G M, Löwik C W G M, Ntziachristos V, Vahrmeijer A L
Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA, Leiden, The Netherlands,
Mol Imaging Biol. 2014 Apr;16(2):147-51. doi: 10.1007/s11307-013-0707-y.
During the European Molecular Imaging Meeting (EMIM) 2013, the fluorescence-guided surgery study group held its inaugural session to discuss the clinical implementation of fluorescence-guided surgery. The general aim of this study group is to discuss and identify the steps required to successfully and safely bring intraoperative fluorescence imaging to the clinics. The focus group intends to use synergies between interested groups as a tool to address regulatory and implementation hurdles in Europe and operates within the intraoperative focus group of the World Molecular Imaging Society (WMIS) that promotes the same interests at the WMIS level. The major topics on the critical path of implementation identified within the study group were quality controls and standards for ensuring accurate imaging and the ability to compare results from different studies, regulatory affairs, and strategies to increase awareness among physicians, regulators, insurance companies, and a broader audience. These hurdles, and the possible actions discussed to overcome them, are summarized in this report. Furthermore, a number of recommendations for the future shape of the fluorescence-guided study group are discussed. A main driving conclusion remains that intraoperative imaging has great clinical potential and that many of the solutions required are best addressed with the community working together to optimally promote and accelerate the clinical implementation of fluorescence imaging towards improving surgical procedures.
在2013年欧洲分子成像会议（EMIM）期间，荧光引导手术研究小组举行了首次会议，以讨论荧光引导手术的临床应用。该研究小组的总体目标是讨论并确定成功且安全地将术中荧光成像引入临床所需的步骤。该焦点小组打算利用各相关团体之间的协同作用，作为解决欧洲监管和实施障碍的工具，并在世界分子成像协会（WMIS）的术中焦点小组内开展工作，该小组在WMIS层面推动相同的利益。研究小组确定的实施关键路径上的主要议题包括确保准确成像以及能够比较不同研究结果的质量控制和标准、监管事务，以及提高医生、监管机构、保险公司和更广泛受众认识的策略。本报告总结了这些障碍以及为克服它们而讨论的可能行动。此外，还讨论了对荧光引导研究小组未来形态的一些建议。一个主要的推动性结论仍然是，术中成像具有巨大的临床潜力，许多所需的解决方案最好通过社区共同努力来最佳地促进和加速荧光成像的临床应用，以改善手术程序。
