Swapnil S Auti, Anup B Thakar, Shukla V J, Ashok B K, Ravishankar B
Ph. D. Scholar, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
Ayu. 2013 Apr;34(2):220-5. doi: 10.4103/0974-8520.119687.
Lekhana Basti (medicated enema) is a Tikshna formulation which is basically aimed for Apatarpana of the body. The present study (medicated enema) was undertaken to evaluate its anti-hyperlipidemic activity in diet-induced hyperlipidemia animals. Parameters like changes in body weight, organ weight, serum total cholesterol, serum triglyceride, serum HDL cholesterol, and serum (LDL + VLDL) cholesterol were studied to assess the effect of therapy in comparison to the control groups. Lekhana Basti was found to be ineffective in producing anti-hyperlipidemic action potently, but still found to have cytoprotective activity against hyperlipidemia induced organ damage, which was also confirmed by attenuation of cell infiltration and microfatty changes on histopathological examination.
莱克哈纳灌肠剂（药用灌肠剂）是一种强效配方，其主要目的是使身体排毒。本研究（药用灌肠剂）旨在评估其在饮食诱导的高脂血症动物中的抗高血脂活性。研究了体重、器官重量、血清总胆固醇、血清甘油三酯、血清高密度脂蛋白胆固醇和血清（低密度脂蛋白+极低密度脂蛋白）胆固醇等参数，以评估与对照组相比治疗的效果。发现莱克哈纳灌肠剂在有效产生抗高血脂作用方面无效，但仍发现其对高脂血症诱导的器官损伤具有细胞保护活性，这也通过组织病理学检查中细胞浸润和微脂肪变化的减轻得到证实。
