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以急性意识模糊状态为表现的维生素B12缺乏症:一例病例报告及文献综述

Vitamin B12 deficiency presenting as an acute confusional state: a case report and review of literature.

作者信息

Kibirige D, Wekesa C, Kaddu-Mukasa M, Waiswa M

机构信息

Department of Medicine, Makerere University College of Health Sciences and Haematology Unit, Mulago National Referral and Teaching hospital, Kampala Uganda.

出版信息

Afr Health Sci. 2013 Sep;13(3):850-2. doi: 10.4314/ahs.v13i3.47.

Abstract

BACKGROUND

Vitamin B12 deficiency is associated with a wide spectrum of neuro-psychiatric manifestations.

RESULTS

We report a case of a 44 year old female patient referred to the haematology unit with vitamin B12 deficiency presenting as an acute confusional state or delirium. Total resolution of the psychiatric symptoms occurred following parenteral vitamin B12 replacement therapy.

CONCLUSION

This case report highlights one of the neuro-psychiatric presentations of vitamin B12 deficiency in a previously healthy individual.

摘要

背景

维生素B12缺乏与广泛的神经精神表现相关。

结果

我们报告一例44岁女性患者,因维生素B12缺乏以急性意识模糊状态或谵妄表现被转诊至血液科。经肠胃外补充维生素B12治疗后,精神症状完全缓解。

结论

本病例报告强调了维生素B12缺乏在一名既往健康个体中的神经精神表现之一。

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本文引用的文献

1
Cognitive impairment and vitamin B12: a review.认知障碍与维生素 B12:综述。
Int Psychogeriatr. 2012 Apr;24(4):541-56. doi: 10.1017/S1041610211002511. Epub 2012 Jan 6.
2
[Clinical spectrum of cobalamin deficiency in Tunisia].
Ann Biol Clin (Paris). 2007 Mar-Apr;65(2):135-42.
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Vitamin B12 for cognition.用于认知的维生素B12。
Cochrane Database Syst Rev. 2003(3):CD004326. doi: 10.1002/14651858.CD004326.
7
Vitamin B12 deficiency.维生素B12缺乏症。
Am Fam Physician. 2003 Mar 1;67(5):979-86.

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