Eydi Mahmood, Kolahdouzan Khosro, Golzari Samad Ej
Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran.
J Cardiovasc Thorac Res. 2013;5(1):29-33. doi: 10.5681/jcvtr.2013.006. Epub 2013 Mar 13.
Postoperative sore throat is a common complication which can lead to discomfort after operation and delay in patients' returning to normal daily activities. The present study was carried out to evaluate the influence of intravenous hydrocortisone on preventing postoperative sore throat followed by laryngeal mask airway use.
Sixty patients who were scheduled to undergo urogenital surgery were divided into two groups. Five minutes before anesthesia induction, 100 mg of intravenous hydrocortisone or placebo with the same volume were given to the patients randomly. At the end of the operation and after LMAs were removed, patients were asked about having sore throat at hours 2, 4 and 24 after operation.
There were three and six cases of sore throat after operation in hydrocortisone and in placebo groups respectively which showed no significant statistical difference (P=0.472). No cases of moderate or severe pain were reported in any of the patients in both groups and no statistically significant difference was observed regarding pain severity in recovery, hours 2, 4 or 24 after operation.
Based on the statistical data obtained from this research, administrating intravenous hydrocortisone five minutes before anesthesia induction has no effect on postoperative sore throat severity and degree in urogenital surgeries.
术后咽喉痛是一种常见并发症,可导致术后不适并延迟患者恢复正常日常活动。本研究旨在评估静脉注射氢化可的松对预防喉罩通气道使用后术后咽喉痛的影响。
将60例计划接受泌尿生殖系统手术的患者分为两组。在麻醉诱导前5分钟,随机给予患者100毫克静脉注射氢化可的松或相同体积的安慰剂。手术结束并拔除喉罩后,询问患者术后2小时、4小时和24小时是否有咽喉痛。
氢化可的松组和安慰剂组术后分别有3例和6例出现咽喉痛,差异无统计学意义(P=0.472)。两组患者均未报告中度或重度疼痛病例,术后恢复2小时、4小时或24小时的疼痛严重程度差异无统计学意义。
根据本研究获得的统计数据,麻醉诱导前5分钟静脉注射氢化可的松对泌尿生殖系统手术的术后咽喉痛严重程度无影响。