术后寒战的管理：哌替啶与氯胺酮的比较
Postoperative Management of Shivering: A Comparison of Pethidine vs. Ketamine.
作者信息
Eydi Mahmood, Golzari Samad Ej, Aghamohammadi Davood, Kolahdouzan Khosro, Safari Saeid, Ostadi Zohreh
机构信息
Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Anesth Pain Med. 2014 Mar 14;4(2):e15499. doi: 10.5812/aapm.15499. eCollection 2014 May.
BACKGROUND
One of the unpleasant side effects of general anesthesia is shivering in the process of recovery. It is an involuntary oscillatory mechanical movement that can be classified as clonic movements. These movements can affect one or several groups of skeletal muscles beginning from 5 to 30 minutes after the discontinuation of anesthesia.
OBJECTIVES
We aimed to study ketamine's effect on shivering after operation compared to pethidine as a way for treatment of postoperative shivering.
PATIENTS AND METHODS
In this study, 60 patients who underwent ENT surgery with general anesthesia and had shivering during recovery were randomly divided into two groups of 30 patients each receiving ketamine (0.2 mg/kg IV) and pethidine (0.5 mg/kg).
RESULTS
There was no statistically significant difference between the shivering intensity in both groups. Only regarding the shivering in the first minute after entering the recovery room, there was an obvious difference between ketamine and pethidine groups which was again not statistically significant (P = 0.07).
CONCLUSIONS
The results of this study showed that ketamine and pethidine are both equally effective in the reduction of postoperative shivering.
背景
全身麻醉令人不适的副作用之一是恢复过程中的寒战。这是一种不自主的振荡性机械运动，可归类为阵挛性运动。这些运动可在麻醉停止后5至30分钟开始影响一组或几组骨骼肌。
目的
我们旨在研究与哌替啶相比，氯胺酮对术后寒战的影响，以此作为治疗术后寒战的一种方法。
患者与方法
在本研究中，60例接受全身麻醉的耳鼻喉科手术患者在恢复过程中出现寒战，随机分为两组，每组30例，分别接受氯胺酮（静脉注射0.2mg/kg）和哌替啶（0.5mg/kg）。
结果
两组寒战强度无统计学显著差异。仅在进入恢复室后的第一分钟寒战情况方面，氯胺酮组和哌替啶组存在明显差异，但同样无统计学意义（P = 0.07）。
结论
本研究结果表明，氯胺酮和哌替啶在减轻术后寒战方面同样有效。
Zotero 插件