尿崩症作为Rathke裂囊肿的首发表现
Diabetes insipidus as a presenting manifestation of Rathke's cleft cyst.
作者信息
Kumar Manoj, Dutta Deep, Shivaprasad K S, Jain Rajesh, Sen Ankita, Biswas Dibakar, Mukhopadhyay Madhumita, Ghosh Sujoy, Mukhopadhyay Satinath, Chowdhury Subhankar
机构信息
Department of Endocrinology and Metabolism, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.
出版信息
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S127-9. doi: 10.4103/2230-8210.119529.
Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesions derived from remnants of Rathke's pouch, lined by cuboidal or columnar epithelium. RCC are usually asymptomatic but can present with headache, visual impairment, panhypopituitarism and hypothalamic dysfunction. Diabetes Insipidus as a presenting symptom of RCC is reported, but rare. We present a case of a 48-year-old male presenting with polyuria and on investigations found to have central diabetes insipidus due to a sellar RCC. Patient underwent transsphenoidal surgery with complete excision with resolution of his symptoms. His polyuria resolved post-surgery without vasopressin replacement, which has never been reported.
拉克氏裂囊肿（RCC）是源于拉克氏囊残余的鞍内和鞍上囊性病变，内衬立方上皮或柱状上皮。RCC通常无症状，但可表现为头痛、视力障碍、全垂体功能减退和下丘脑功能障碍。有报道称尿崩症作为RCC的首发症状，但较为罕见。我们报告一例48岁男性，因多尿就诊，经检查发现因鞍区RCC导致中枢性尿崩症。患者接受经蝶窦手术，肿瘤完全切除，症状缓解。术后其多尿症状自行缓解，无需使用血管加压素替代治疗，此前未见此类报道。
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