Panchani Roopal, Varma Tarun, Goyal Ashutosh, Tripathi Sudhir
Department of Endocrinology, Sir Ganga Ram Hospital, New Delhi, India.
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S135-8. doi: 10.4103/2230-8210.119533.
Pituitary masses usually present as sellar masses with suprasellar or parasellar extension. However, in unusual cases pituitary tumors especially macroprolactinomas and nonfunctional adenomas can present with intranasal extension which can be misdiagnosed as nasal polyp or a primary invasive nasopharyngeal malignant tumor. The otolaryngologists should be familiar with this rare presentation of pituitary masses. Measurement of prolactin (PRL) is essential in cases of recalcitrant nasal polyps or rhinorrhea as it may change the management in such cases. Here we describe case of a patient with an invasive pituitary adenoma who had presented in the otorhinolaryngology department with a nasal obstruction and epistaxis. We have also reviewed 30 cases of pituitary adenoma with nasopharyngeal invasion published in past.
垂体肿块通常表现为鞍区肿块，并向鞍上或鞍旁延伸。然而，在一些特殊情况下，垂体肿瘤尤其是大泌乳素瘤和无功能腺瘤可呈鼻内延伸，这可能被误诊为鼻息肉或原发性侵袭性鼻咽恶性肿瘤。耳鼻喉科医生应熟悉垂体肿块这种罕见的表现形式。对于顽固性鼻息肉或鼻漏病例，测定泌乳素（PRL）至关重要，因为这可能会改变此类病例的治疗方案。在此，我们描述了一例侵袭性垂体腺瘤患者，该患者因鼻塞和鼻出血就诊于耳鼻喉科。我们还回顾了过去发表的30例垂体腺瘤侵犯鼻咽的病例。
