Jakka Nagendar, Venkateshwarlu J, Satyavani Naga, Neelaveni K, Ramesh Jayanthy
Department of Endocrinology, Osmania Medical College, Osmania General Hospital, Afzalgunj Hyderabad, Andhra Pradesh, India.
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S249-51. doi: 10.4103/2230-8210.119588.
Co-occurrence of adrenal incidentaloma with hypertension calls for evaluation of endocrine causes including pheochromocytoma, Cushing's disease, and primary aldosteronism. We are reporting 40-years-old man who presented with hypertension and adrenal mass. He had elevated metanephrines, histology of resected adrenal mass revealed adrenal myelolipoma, and immuno-histochemistry was positive for chromogranin A. Both his blood pressure and urinary metanephrines returned to normal after surgery. The association of hypertension and adrenal myelolipoma may not be entirely coincidental, as it may be associated with secreting catecholamine. Literature on such an uncommon association is reviewed briefly as well.
肾上腺偶发瘤合并高血压需要评估包括嗜铬细胞瘤、库欣病和原发性醛固酮增多症在内的内分泌病因。我们报告一名40岁男性，他患有高血压和肾上腺肿块。他的间甲肾上腺素升高，切除的肾上腺肿块组织学检查显示为肾上腺髓质脂肪瘤，免疫组化嗜铬粒蛋白A呈阳性。术后他的血压和尿间甲肾上腺素均恢复正常。高血压与肾上腺髓质脂肪瘤的关联可能并非完全偶然，因为它可能与儿茶酚胺分泌有关。本文也简要回顾了关于这种罕见关联的文献。
