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1型糖尿病中的心血管风险

Cardiovascular risk in type 1 diabetes mellitus.

作者信息

Slim Ines Ben Hadj Slama

机构信息

Department of Endocrinology and Diabetes, Farhat Hached Hospital, Sousse, Tunisia.

出版信息

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S7-S13. doi: 10.4103/2230-8210.119489.

DOI:10.4103/2230-8210.119489
PMID:24251225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830372/
Abstract

Commonly cardiovascular risk (CVR) is linked to type 2 diabetes mellitus as this type is known to be part of the metabolic syndrome, which includes other cardiovascular factors such as hypertension, dyslipidemia. Inversely, CVR of type 1 diabetes mellitus (T1DM) is currently being debated apart from the occurrence of diabetic nephropathy (DN). For this, we did a review of CVR in patients with T1DM complicated or not with DN. The place of novel non-invasive techniques in screening of subclinical vascular damage is also discussed in this review.

摘要

心血管风险（CVR）通常与2型糖尿病相关，因为已知该型糖尿病是代谢综合征的一部分，代谢综合征还包括其他心血管因素，如高血压、血脂异常。相反，1型糖尿病（T1DM）的CVR目前除了糖尿病肾病（DN）的发生外仍存在争议。为此，我们对合并或未合并DN的T1DM患者的CVR进行了综述。本综述还讨论了新型非侵入性技术在亚临床血管损伤筛查中的作用。

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本文引用的文献

1
Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort study.1 型糖尿病患者死亡率的时间趋势：全国基于人群的队列研究。
BMJ. 2011 Sep 8;343:d5364. doi: 10.1136/bmj.d5364.
2
The effect of cardiovascular risk factors on the longitudinal evolution of the carotid intima medial thickness in children with type 1 diabetes mellitus.心血管危险因素对 1 型糖尿病患儿颈动脉内膜中层厚度纵向演变的影响。
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3
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.极长期 1 型糖尿病患者的视网膜病变和其他并发症的保护：Joslin 50 年奖章研究。
Diabetes Care. 2011 Apr;34(4):968-74. doi: 10.2337/dc10-1675.
4
All-cause mortality trends in a large population-based cohort with long-standing childhood-onset type 1 diabetes: the Allegheny County type 1 diabetes registry.在一个大型基于人群的、具有长期儿童发病 1 型糖尿病的队列中，全因死亡率趋势：阿勒格尼县 1 型糖尿病登记处。
Diabetes Care. 2010 Dec;33(12):2573-9. doi: 10.2337/dc10-1170.
5
Carotid intima-media thickness and arterial stiffness in type 1 diabetic patients are dependent on age and mean blood pressure.1型糖尿病患者的颈动脉内膜中层厚度和动脉僵硬度取决于年龄和平均血压。
Exp Clin Endocrinol Diabetes. 2011 May;119(5):281-5. doi: 10.1055/s-0030-1267184. Epub 2010 Oct 28.
6
Evolution and predictors of morphological and functional arterial changes in the course of type 1 diabetes mellitus.1 型糖尿病病程中形态和功能动脉变化的演变及其预测因素。
Diabetes Metab Res Rev. 2010 Nov;26(8):646-55. doi: 10.1002/dmrr.1133. Epub 2010 Oct 4.
7
Cause-specific mortality trends in a large population-based cohort with long-standing childhood-onset type 1 diabetes.基于大型人群队列的长期儿童起病 1 型糖尿病患者的病因特异性死亡率趋势。
Diabetes. 2010 Dec;59(12):3216-22. doi: 10.2337/db10-0862. Epub 2010 Aug 25.
8
Endothelial abnormalities in adolescents with type 1 diabetes: a biomarker for vascular sequelae?青少年 1 型糖尿病患者的血管内皮异常：血管并发症的生物标志物？
J Pediatr. 2010 Oct;157(4):540-6. doi: 10.1016/j.jpeds.2010.04.050. Epub 2010 Jun 12.
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Insulin resistance in adolescents with type 1 diabetes and its relationship to cardiovascular function.青少年 1 型糖尿病患者的胰岛素抵抗及其与心血管功能的关系。
J Clin Endocrinol Metab. 2010 Feb;95(2):513-21. doi: 10.1210/jc.2009-1756. Epub 2009 Nov 13.
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Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes--the 'dead in bed' syndrome revisited.1型糖尿病患者的心律失常与夜间低血糖——再探“床上猝死”综合征
Diabetologia. 2009 Jan;52(1):42-5. doi: 10.1007/s00125-008-1177-7. Epub 2008 Oct 30.