用99mTc(V)-二巯基丁二酸进行闪烁扫描术监测炎症性肠病患者。
Scintigraphy with 99mTc(V)-DMSA in monitoring patients with inflammatory bowel disease.
作者信息
Javadi Hamid, Amiriani Taghi, Mirkarimi HoneySadat, Besharat Sima, Semnani Shahriar, Abedi Jamshid, Seyedabadi Mohammad, Assadi Majid
机构信息
The Persian Gulf Nuclear Medicine Research Center, The Persian Gulf Biomedical Sciences Institute, Boostan 19 Alley, Sangi Street, Bushehr, Iran.
出版信息
Hell J Nucl Med. 2013 Sep-Dec;16(3):209-12.
The clinical significance of pentavalent technetium-99m dimercaptosuccinic acid (99mTc(V)-DMSA) scintigraphy in diagnosing inflammatory bowel disease (IBD) has not yet been fully elucidated. The aim of this prospective paper was to study the above. This study included 54 patients, 22 females and 32 males (mean age: 36.68±11.49; range: 18-63 years) with IBD who came to our clinics for follow-up and were examined clinically by colonoscopy and 99mTc(V)-DMSA scintigraphy. On the follow-up studies, five patients (9.25%) relapsed, and 49 (90.74%) remained at a steady condition. There was a good correlation between the scintigraphic results and the clinical and colonoscopy data of the patients (P<0.05). In conclusion, our results indicated that 99mTc(V)DMSA scintigraphy can be complementary to colonoscopy for the diagnostic evaluation of IBD.
五价锝-99m二巯基丁二酸（99mTc(V)-DMSA）闪烁扫描术在诊断炎症性肠病（IBD）中的临床意义尚未完全阐明。这篇前瞻性论文的目的是研究上述内容。本研究纳入了54例IBD患者，其中女性22例，男性32例（平均年龄：36.68±11.49岁；范围：18 - 63岁），这些患者前来我们诊所进行随访，并接受了结肠镜检查和99mTc(V)-DMSA闪烁扫描术的临床检查。在随访研究中，5例患者（9.25%）复发，49例（90.74%）病情稳定。闪烁扫描结果与患者的临床及结肠镜检查数据之间存在良好的相关性（P<0.05）。总之，我们的结果表明，99mTc(V)DMSA闪烁扫描术可作为结肠镜检查的补充手段，用于IBD的诊断评估。
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