锝-99m（V）二巯基丁二酸（DMSA）闪烁扫描术在缺血性结肠炎中是否有作用？
Is there a role for Tc-99m (V) DMSA scintigraphy in ischemic colitis?
作者信息
Stathaki Maria I, Koutroubakis Ioannis E, Koukouraki Sophia I, Kouroumalis Elias A, Karkavitsas Nikolaos S
机构信息
University Hospital Heraklion, Department of Gastroenterology, Heraklion, Crete, Greece.
出版信息
World J Gastroenterol. 2008 Sep 21;14(35):5432-5. doi: 10.3748/wjg.14.5432.
AIM
To evaluate the role of pentavalent Tc-99m dimercaptosuccinic acid [Tc-99m (V) DMSA] in the diagnosis of ischemic colitis.
METHODS
Fourteen patients with endoscopically and histologically confirmed ischemic colitis were included in the study. Tc-99m (V) DMSA scintigraphy was performed within 2 d after colonoscopy. Images were considered positive when an area of increased activity was observed in the region of interest and negative when no abnormal tracer uptake was detected.
RESULTS
In 3 out of the 14 patients, Tc-99m (V) DMSA images showed moderate activity in the bowel. The scintigraphic results corresponded with the endoscopic findings. In the other 11 patients, no abnormal tracer uptake was detected in the abdomen.
CONCLUSION
Besides the limited number of patients, Tc-99m (V) DMSA could not be considered as a useful imaging modality for the evaluation of ischemic colitis.
目的
评估五价锝-99m二巯基丁二酸[锝-99m（V）DMSA]在缺血性结肠炎诊断中的作用。
方法
本研究纳入了14例经内镜和组织学确诊为缺血性结肠炎的患者。在结肠镜检查后2天内进行锝-99m（V）DMSA闪烁扫描。当在感兴趣区域观察到活性增加区域时，图像被视为阳性；当未检测到异常示踪剂摄取时，图像被视为阴性。
结果
14例患者中有3例，锝-99m（V）DMSA图像显示肠道有中度活性。闪烁扫描结果与内镜检查结果相符。在其他11例患者中，腹部未检测到异常示踪剂摄取。
结论
除患者数量有限外，锝-99m（V）DMSA不能被视为评估缺血性结肠炎的有用成像方式。
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