1型糖尿病患儿黄斑中心凹下脉络膜厚度的评估：一项增强深度成像光学相干断层扫描（EDI-OCT）研究
Evaluation of subfoveal choroidal thickness in children with type 1 diabetes mellitus: an EDI-OCT study.
作者信息
Sayin Nihat, Kara Necip, Pirhan Dilara, Vural Asli, Ersan Hatice Bilge Araz, Onal Hasan, Cınar Simge
机构信息
Department of Ophthalmology, Kanuni Sultan Suleyman Education and Research Hospital , Istanbul , Turkey .
出版信息
Semin Ophthalmol. 2014 Jan;29(1):27-31. doi: 10.3109/08820538.2013.838279. Epub 2013 Nov 19.
PURPOSE
To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in children with type 1 diabetes without diabetic retinopathy.
METHODS
In this prospective and comparative study, 41 diabetic children without diabetic retinopathy and 42 age-matched healthy subjects were enrolled. The SFCT was measured by EDI-OCT. Correlations between SFCT and diabetic parameters such as fasting glucose level, HbA1c, age, or duration of diabetes were also evaluated.
RESULTS
The mean SFCT value was 375.3 ± 66.5 μm in the eyes with diabetes and 356.4 ± 52.0 μm in the control group. The SFCT was not correlated with fasting glucose level, HbA1c, age, or duration of diabetes.
CONCLUSION
This study showed that SFCT of diabetic children are similar to those of healthy controls. In addition, SFCT are not affected by fasting glucose level, HbA1c, age, or duration of diabetes.
目的
评估采用增强深度成像光学相干断层扫描（EDI-OCT）测量的1型糖尿病且无糖尿病视网膜病变患儿的黄斑中心凹下脉络膜厚度（SFCT）。
方法
在这项前瞻性对照研究中，纳入了41例无糖尿病视网膜病变的糖尿病患儿和42例年龄匹配的健康受试者。采用EDI-OCT测量SFCT。还评估了SFCT与糖尿病参数（如空腹血糖水平、糖化血红蛋白、年龄或糖尿病病程）之间的相关性。
结果
糖尿病组患儿眼睛的平均SFCT值为375.3±66.5μm，对照组为356.4±52.0μm。SFCT与空腹血糖水平、糖化血红蛋白、年龄或糖尿病病程均无相关性。
结论
本研究表明，糖尿病患儿的SFCT与健康对照者相似。此外，SFCT不受空腹血糖水平、糖化血红蛋白、年龄或糖尿病病程的影响。
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