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单纯肘管减压术治疗肘管尺神经病变术后功能预后的预测因素:SUN 研究组的一项多中心研究。

Predictors of functional outcomes after simple decompression for ulnar neuropathy at the elbow: a multicenter study by the SUN study group.

机构信息

Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI.

Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, MI.

出版信息

Arch Phys Med Rehabil. 2014 Apr;95(4):680-5. doi: 10.1016/j.apmr.2013.10.028. Epub 2013 Nov 16.

Abstract

OBJECTIVE

To identify predictors of surgical outcome for ulnar neuropathy at the elbow (UNE).

DESIGN

Prospective cohort followed for 1 year.

SETTING

Clinics.

PARTICIPANTS

Patients diagnosed with UNE (N=55).

INTERVENTION

All subjects had simple decompression surgery.

MAIN OUTCOME MEASURES

The primary outcome measure was patient-reported outcomes, such as overall hand function through the Michigan Hand Outcomes Questionnaire (MHQ). Predictors included age, duration of symptoms, disease severity, and motor conduction velocity across the elbow.

RESULTS

Multiple regression models with change in the overall MHQ score as the dependent variable showed that at 3 months postoperative time, patients with <3 months duration of symptoms showed 12 points (95% confidence interval [CI], 0.9-23.5) greater improvement in MHQ scores than those with ≥3 months symptom duration. Less than 3 months of symptoms was again associated with 13 points (95% CI, 2.9-24) greater improvement in MHQ scores at 6 months postoperative, but it was no longer associated with better outcomes at 12 months. A worse baseline MHQ score was associated with significant improvement in MHQ scores at 3 months (coefficient, -0.38; 95% CI, -.67 to -.09), and baseline MHQ score was the only significant predictor of 12 month MHQ scores (coefficient, -.40; 95% CI, -.79 to -.01).

CONCLUSIONS

Subjects with <3 months of symptoms and worse baseline MHQ scores showed significantly greater improvement in functional outcomes as reported by the MHQ. However, duration of symptoms was only predictive at 3 or 6 months because most patients recovered within 3 to 6 months after surgery.

摘要

目的

确定肘管综合征(UNE)手术结果的预测因素。

设计

前瞻性队列研究,随访 1 年。

地点

诊所。

参与者

诊断为 UNE 的患者(N=55)。

干预

所有患者均行单纯减压手术。

主要观察指标

主要观察指标为患者报告的结果,如通过密歇根手功能问卷(MHQ)评估的整体手部功能。预测因素包括年龄、症状持续时间、疾病严重程度和肘部运动传导速度。

结果

以整体 MHQ 评分变化为因变量的多元回归模型显示,术后 3 个月时,症状持续时间<3 个月的患者 MHQ 评分改善 12 分(95%置信区间[CI],0.9-23.5),而症状持续时间≥3 个月的患者 MHQ 评分改善 12 分(95%CI,0.9-23.5)。<3 个月的症状再次与术后 6 个月 MHQ 评分改善 13 分(95%CI,2.9-24)相关,但与 12 个月时的更好结果不再相关。基线 MHQ 评分较低与术后 3 个月 MHQ 评分显著改善相关(系数,-0.38;95%CI,-0.67 至-0.09),且基线 MHQ 评分是 12 个月 MHQ 评分的唯一显著预测因素(系数,-0.40;95%CI,-0.79 至-0.01)。

结论

症状持续时间<3 个月且基线 MHQ 评分较低的患者,MHQ 报告的功能结果改善显著更大。然而,症状持续时间仅在 3 或 6 个月时具有预测性,因为大多数患者在手术后 3 至 6 个月内恢复。

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