支气管动脉栓塞术治疗肿瘤所致咯血的结果

Results of bronchial artery embolization for the treatment of hemoptysis caused by neoplasm.

作者信息

Garcia-Olivé Ignasi, Sanz-Santos Jose, Centeno Carmen, Andreo Felipe, Muñoz-Ferrer Aida, Serra Pere, Sampere Jaume, Michavila Josep Maria, Muchart Jordi, Manzano Juan Ruiz

机构信息

Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona; CibeRes-Ciber de Enfermedades Respiratorias, Bunyola, Bunyola, Mallorca.

出版信息

J Vasc Interv Radiol. 2014 Feb;25(2):221-8. doi: 10.1016/j.jvir.2013.09.017. Epub 2013 Nov 16.

DOI:10.1016/j.jvir.2013.09.017

PMID:24252773

Abstract

PURPOSE

To describe experience with bronchial artery embolization (BAE) in a cohort of patients with cancer.

MATERIALS AND METHODS

All consecutive patients with cancer and at least one episode of hemoptysis that required BAE during a 14-year period were included in this observational retrospective review. The endpoints of the study were immediate success, recurrence of hemoptysis, mortality resulting from hemoptysis, and all-cause mortality.

RESULTS

Immediate control of bleeding was achieved in 31 of 40 patients (77.5%). Recurrence requiring BAE occurred in eight patients (20%). Cumulative hemoptysis control rate was 0.90 (95% confidence interval [CI], 0.80-1.0) at 1 month and 0.65 (95% CI, 0.44-0.86) at 6 months. Probability of survival was 0.75 (95% CI, 0.62-0.88) at 1 month, 0.42 (95% CI, 0.27-0.57) at 6 months, 0.36 (95% CI, 0.21-0.51) at 12 months, and 0.08 (95% CI, 0.0-0.18) at 3 years.

CONCLUSIONS

BAE is an effective and safe technique in the treatment of hemoptysis in patients with cancer. Nevertheless, mortality resulting from hemoptysis and recurrence rate are high among these patients secondary to progression of the underlying disease.

摘要

目的

描述一组癌症患者接受支气管动脉栓塞术（BAE）的经验。

材料与方法

本观察性回顾性研究纳入了在14年期间所有连续的患有癌症且至少有一次咯血发作需要进行BAE的患者。研究终点为即刻成功、咯血复发、咯血导致的死亡率以及全因死亡率。

结果

40例患者中有31例（77.5%）实现了出血的即刻控制。8例患者（20%）出现需要再次进行BAE的复发情况。1个月时咯血累积控制率为0.90（95%置信区间[CI]，0.80 - 1.0），6个月时为0.65（95%CI，0.44 - 0.86）。1个月时生存概率为0.75（95%CI，0.62 - 0.88），6个月时为0.42（95%CI，0.27 - 0.57），12个月时为0.36（95%CI，0.21 - 0.51），3年时为0.08（95%CI，0.0 - 0.18）。