Loukeri Angeliki A, Pantazopoulos Ioannis N, Tringidou Rodoula, Giampoudakis Pantelis, Valaskatzi Argyro, Loukeri Pinelopi A, Kampolis Christos F
Respiratory Intensive Care Unit
12th Respiratory Medicine Department.
Respir Care. 2014 Jul;59(7):e94-7. doi: 10.4187/respcare.02775. Epub 2013 Nov 19.
Benign metastasizing leiomyoma (BML) was initially used to describe single or multiple pulmonary nodules composed of proliferating smooth muscle cells (lacking cellular atypia) in premenopausal females 3 months to 20 y after hysterectomy for uterine leiomyoma. The lung is the most commonly involved site, thus including many malignant and benign entities in the differential diagnosis. The present case refers to a 47-y-old premenopausal woman with a history of subtotal hysterectomy for a uterine leiomyoma presenting with bilateral cavitating pulmonary nodules. A number of nodules were resected by video-assisted thoracoscopic surgery. The histological findings in correlation with the immunohistochemical results were consistent with the diagnosis of BML. A bilateral salpingo-oophorectomy was performed, combined with complete removal of the remaining cervix. One year later, the subject remains asymptomatic, and the pulmonary nodules are stable with regard to number, size, location, and morphology.
良性转移性平滑肌瘤（BML）最初用于描述绝经前女性在子宫平滑肌瘤子宫切除术后3个月至20年出现的由增殖性平滑肌细胞（缺乏细胞异型性）组成的单个或多个肺结节。肺是最常受累的部位，因此在鉴别诊断中包括许多恶性和良性病变。本病例为一名47岁绝经前女性，有子宫平滑肌瘤次全子宫切除病史，现出现双侧空洞性肺结节。通过电视辅助胸腔镜手术切除了多个结节。组织学检查结果与免疫组化结果一致，符合BML的诊断。进行了双侧输卵管卵巢切除术，并完整切除了剩余的宫颈。一年后，该患者仍无症状，肺结节在数量、大小、位置和形态方面保持稳定。
